Clinical Presentation and Outcome Differences Between Black Patients and Patients of Other Races and Ethnicities With Mycosis Fungoides and Sézary Syndrome.
Sign Up to like & getrecommendations! Published in 2022 at "JAMA dermatology"
DOI: 10.1001/jamadermatol.2022.3601
Abstract: Importance Mycosis fungoides and Sézary syndrome (MF/SS) has an increased incidence in Black patients, but clinical characteristics, treatments, and outcomes have been poorly characterized. Objective To assess racial differences in presentation and outcome and identify… read more here.
Keywords: black patients; zary syndrome; presentation; fungoides zary ... See more keywords
Mycosis Fungoides and Sézary Syndrome: Updates and Review of Current Therapy
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DOI: 10.1007/s11864-020-00809-w
Abstract: While most patients with early-stage mycosis fungoides (MF) follow an indolent course, patients with advanced-stage MF/Sézary syndrome (SS) have a poor prognosis with a median survival of less than 5 years. Although there are a… read more here.
Keywords: zary syndrome; mycosis fungoides; advanced stage; therapy ... See more keywords
Systemic Treatment Options for Advanced-Stage Mycosis Fungoides and Sézary Syndrome
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DOI: 10.1007/s11912-018-0678-x
Abstract: Purpose of ReviewCutaneous T-cell lymphoma (CTCL) is a rare form of non-Hodgkin lymphoma. Globally, the most common subtypes of CTCL are mycosis fungoides and Sézary syndrome. CTCL can confer significant morbidity and even mortality in… read more here.
Keywords: systemic treatment; fungoides zary; zary syndrome; treatment ... See more keywords
COVID-19 infection in patients with Sézary syndrome: report of three cases
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DOI: 10.1016/s0959-8049(21)00756-5
Abstract: Introduction: A severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spread worldwide during 2020, was declared as a public health emergency and potentially life-threatening. Patients with hematologic malignancies may have an increased risk of severe COVID-19,… read more here.
Keywords: zary syndrome; case; infection; disease ... See more keywords
Blockade of programmed cell death protein 1 (PD-1) in Sézary syndrome reduces Th2 phenotype of non-tumoral T lymphocytes but may enhance tumor proliferation
Sign Up to like & getrecommendations! Published in 2020 at "Oncoimmunology"
DOI: 10.1080/2162402x.2020.1738797
Abstract: ABSTRACT Sézary syndrome (SS) is an aggressive leukemic variant of cutaneous T-cell lymphoma (L-CTCL) that arises from malignant clonally derived skin-homing CD4+ T cells. Based on advancements in our understanding of the mechanisms underlying L-CTCL,… read more here.
Keywords: zary syndrome; th2 phenotype; phenotype non; cell ... See more keywords
Single-cell RNA-sequencing reveals predictive features of response to pembrolizumab in Sézary syndrome
Sign Up to like & getrecommendations! Published in 2022 at "Oncoimmunology"
DOI: 10.1080/2162402x.2022.2115197
Abstract: ABSTRACT The PD-1 inhibitor pembrolizumab is effective in treating Sézary syndrome, a leukemic variant of cutaneous T-cell lymphoma. Our purpose was to investigate the effects of pembrolizumab on healthy and malignant T cells in Sézary… read more here.
Keywords: cell; zary syndrome; rna; single cell ... See more keywords
A case of Sézary syndrome in a patient during treatment with baricitinib for seronegative rheumatoid arthritis.
Sign Up to like & getrecommendations! Published in 2022 at "Clinical and experimental dermatology"
DOI: 10.1093/ced/llac124
Abstract: The risk of developing malignancies including cutaneous T-cell lymphoma with use of Janus kinase inhibitors is of concern. Here, we describe a case of Sézary syndrome in a patient during treatment with baricitinib for seronegative… read more here.
Keywords: baricitinib seronegative; zary syndrome; syndrome patient; treatment baricitinib ... See more keywords
Brentuximab induced splinter nail haemorrhages in a patient with Sézary syndrome: a case report.
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DOI: 10.1111/bcp.15247
Abstract: Sézary syndrome is a systemic variant of cutaneous T-cell lymphoma (CTCL) characterized by erythroderma, lymphadenopathy, and circulating atypical lymphocytes (Sézary cells). It may present with nonspecific lesions on multiple digits. We describe an atypical case… read more here.
Keywords: splinter nail; induced splinter; brentuximab induced; brentuximab ... See more keywords
Characteristics and outcomes of 727 patients with mycosis fungoides and Sézary syndrome from a Brazilian cohort.
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DOI: 10.1111/ijd.15865
Abstract: BACKGROUND Mycosis fungoides (MF) and Sézary syndrome (SS) are the most prevalent cutaneous lymphomas. They were not described in a large Brazilian cohort yet. We aimed, with this single-center, retrospective cohort analysis, to describe the… read more here.
Keywords: fungoides zary; zary syndrome; brazilian cohort; mycosis fungoides ... See more keywords
Epidemiology and prognostic factors for mycosis fungoides and Sézary syndrome in a multi‐ethnic Asian cohort: a 12‐year review
Sign Up to like & getrecommendations! Published in 2019 at "Journal of the European Academy of Dermatology and Venereology"
DOI: 10.1111/jdv.15526
Abstract: Limited information exists regarding survival of Asian patients with mycosis fungoides (MF) and Sézary syndrome (SS). read more here.
Keywords: fungoides zary; zary syndrome; epidemiology prognostic; prognostic factors ... See more keywords
Single-Cell Profiling of Cutaneous T-Cell Lymphoma Reveals Underlying Heterogeneity Associated with Disease Progression
Sign Up to like & getrecommendations! Published in 2019 at "Clinical Cancer Research"
DOI: 10.1158/1078-0432.ccr-18-3309
Abstract: Purpose: Cutaneous T-cell lymphomas (CTCL), encompassing a spectrum of T-cell lymphoproliferative disorders involving the skin, have collectively increased in incidence over the last 40 years. Sézary syndrome is an aggressive form of CTCL characterized by… read more here.
Keywords: zary syndrome; cutaneous cell; cell; disease ... See more keywords