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   Articles with "zbtb11" as a keyword



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ZBTB11 IS REQUIRED FOR HEMATOPOIETIC STEM CELL FUNCTION

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recommendations! Published in 2019 at "Experimental Hematology"

DOI: 10.1016/j.exphem.2019.06.376

Abstract: Hematopoiesis orchestrates the daily requirement of producing and maintaining the various blood cell lineages in the right quantities. It must also respond rapidly to injury and infection to expand specific lineages on demand then return… read more here.

Keywords: required hematopoietic; zbtb11; hematopoiesis; zbtb11 required ... See more keywords
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Intellectual disability-associated factor Zbtb11 cooperates with NRF-2/GABP to control mitochondrial function

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recommendations! Published in 2020 at "Nature Communications"

DOI: 10.1038/s41467-020-19205-x

Abstract: Zbtb11 is a conserved transcription factor mutated in families with hereditary intellectual disability. Its precise molecular and cellular functions are currently unknown, precluding our understanding of the aetiology of this disease. Using a combination of… read more here.

Keywords: intellectual disability; mitochondrial function; factor; zbtb11 ... See more keywords
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ZBTB11 dysfunction: spectrum of brain abnormalities, biochemical signature and cellular consequences

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recommendations! Published in 2022 at "Brain"

DOI: 10.1093/brain/awac034

Abstract: Abstract Bi-allelic pathogenic variants in ZBTB11 have been associated with intellectual developmental disorder, autosomal recessive 69 (MRT69; OMIM 618383). We report five patients from three families with novel, bi-allelic variants in ZBTB11. We have expanded… read more here.

Keywords: mitochondrial functions; dysfunction spectrum; brain; zbtb11 dysfunction ... See more keywords
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Spatial transcriptomics unveils ZBTB11 as a regulator of cardiomyocyte degeneration in arrhythmogenic cardiomyopathy

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recommendations! Published in 2022 at "Cardiovascular Research"

DOI: 10.1093/cvr/cvac072

Abstract: Abstract Aims Arrhythmogenic cardiomyopathy (ACM) is an inherited cardiac disorder that is characterized by progressive loss of myocardium that is replaced by fibro-fatty cells, arrhythmias, and sudden cardiac death. While myocardial degeneration and fibro-fatty replacement… read more here.

Keywords: degeneration; fibro fatty; arrhythmogenic cardiomyopathy; gene expression ... See more keywords