Ultrasound enhances ZD2767P‒carboxypeptidase G2 against chemoresistant ovarian cancer cells by altering the intracellular pharmacokinetics of ZD2767D.
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DOI: 10.1021/acs.molpharmaceut.0c00008
Abstract: Prodrug‒carboxypeptidase G2 (e.g., ZD2767P+CPG2) can realize a targeted treatment where the specific advantage is a lack of CPG2 analogs in humans, but it is limited by low efficacy. Here ultrasound was employed to enhance ZD2767P+CPG2… read more here.
Keywords: cpg2; ovarian cancer; cancer cells; zd2767p cpg2 ... See more keywords