Palmitoyltransferase ZDHHC21 regulates oxidative phosphorylation to induce differentiation block and stemness in AML.
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DOI: 10.1182/blood.2022019056
Abstract: Acute myeloid leukemia (AML) is an aggressive hematological malignancy. Nearly 50% of patients who receive the most intensive treatment inevitably suffer disease relapse, likely resulting from the persistence of drug‑resistant leukemia stem cells (LSCs). AML… read more here.
Keywords: zdhhc21; palmitoyltransferase; aml cells; oxidative phosphorylation ... See more keywords