TCF4 promotes colorectal cancer drug resistance and stemness via regulating ZEB1/ZEB2 expression
Sign Up to like & getrecommendations! Published in 2020 at "Protoplasma"
DOI: 10.1007/s00709-020-01480-6
Abstract: The present study aims to investigate the roles of TCF4 and its underlying mechanism in colorectal cancer (CRC). Doxorubicin-resistant DLD-1 (DLD1 DR), TCF4 overexpression, and TCF4 knockdown cell lines were constructed. A flow cytometer was… read more here.
Keywords: tcf4; zeb1 zeb2; resistance; doxorubicin ... See more keywords
Expression Profiling of EMT Transcriptional Regulators ZEB1 and ZEB2 in Different Histopathological Grades of Oral Squamous Cell Carcinoma Patients
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DOI: 10.2174/0113892029284920240212091903
Abstract: Background Pakistan has a high burden of oral cancers, with a prevalence rate of around 9%. Oral Squamous Cell Carcinoma (OSCC) accounts for about 90% of oral cancer cases. Epithelial to Mesenchymal Transition (EMT) gets… read more here.
Keywords: cancer; expression profiling; zeb1 zeb2; squamous cell ... See more keywords
Role of ZEB family members in proliferation, metastasis and chemoresistance of prostate cancer cells: Revealing signaling networks.
Sign Up to like & getrecommendations! Published in 2021 at "Current cancer drug targets"
DOI: 10.2174/1568009621666210601114631
Abstract: Prostate cancer (PCa) is one of the leading causes of death worldwide. A variety of strategies including surgery, chemotherapy, radiotherapy and immunotherapy are applied for PCa treatment. PCa cells are responsive towards therapy at early… read more here.
Keywords: family members; zeb family; zeb1 zeb2; cancer cells ... See more keywords