LAUSR

About LAUSR
Donate
Contact Us

Follow us:

You are not signed in:

Sign Up!


   Articles with "zeb2" as a keyword



Photo by art_almighty from unsplash

Long non-coding RNA XIST promotes TGF-β-induced epithelial-mesenchymal transition by regulating miR-367/141-ZEB2 axis in non-small-cell lung cancer.

Sign Up to like & get
recommendations! Published in 2018 at "Cancer letters"

DOI: 10.1016/j.canlet.2018.01.036

Abstract: Growing evidence shows that lncRNA XIST functions as an oncogene accelerating tumor progression. Transforming growth factor β (TGF-β)-induced epithelial-mesenchymal transition (EMT) plays a key role in tumor metastasis. However, it is still unclear whether lncRNA… read more here.

Keywords: zeb2; xist; mir 367; tgf induced ... See more keywords
Photo by fahim_junaid from unsplash

The Transcription Factor ZEB2 Is Required to Maintain the Tissue-Specific Identities of Macrophages

Sign Up to like & get
recommendations! Published in 2018 at "Immunity"

DOI: 10.1016/j.immuni.2018.07.004

Abstract: SUMMARY Heterogeneity between different macrophage populations has become a defining feature of this lineage. However, the conserved factors defining macrophages remain largely unknown. The transcription factor ZEB2 is best described for its role in epithelial… read more here.

Keywords: identities macrophages; specific identities; zeb2; tissue specific ... See more keywords
Photo from archive.org

Mowat-Wilson syndrome: Generation of two human iPS cell lines (UUIGPi004A and UUIGPi005A) from siblings with a truncating ZEB2 gene variant.

Sign Up to like & get
recommendations! Published in 2019 at "Stem cell research"

DOI: 10.1016/j.scr.2019.101518

Abstract: Mowat-Wilson syndrome (MWS) is a complex developmental syndrome caused by heterozygous mutations in the Zinc finger E-box-binding homeobox 2 gene (ZEB2). We generated the first human iPSC lines from primary fibroblasts of two siblings with… read more here.

Keywords: zeb2; cell; mowat wilson; ipsc lines ... See more keywords
Photo from wikipedia

An FBXW7-ZEB2 axis links EMT and tumour microenvironment to promote colorectal cancer stem cells and chemoresistance

Sign Up to like & get
recommendations! Published in 2019 at "Oncogenesis"

DOI: 10.1038/s41389-019-0125-3

Abstract: Colorectal cancer (CRC) patients develop recurrence after chemotherapy owing to the survival of stem cell-like cells referred to as cancer stem-like cells (CSCs). The origin of CSCs is linked to the epithelial–mesenchymal transition (EMT) process.… read more here.

Keywords: zeb2; cancer stem; colorectal cancer; cancer ... See more keywords
Photo by wulcan from unsplash

An Nfil3–Zeb2–Id2 pathway imposes Irf8 enhancer switching during cDC1 development

Sign Up to like & get
recommendations! Published in 2019 at "Nature immunology"

DOI: 10.1038/s41590-019-0449-3

Abstract: Classical type 1 dendritic cells (cDC1s) are required for antiviral and antitumor immunity, which necessitates an understanding of their development. Development of the cDC1 progenitor requires an E-protein-dependent enhancer located 41 kilobases downstream of the transcription… read more here.

Keywords: enhancer; zeb2; cdc1 development; development ... See more keywords

Critical involvement of ZEB2 in collagen fibrillogenesis: the molecular similarity between Mowat-Wilson syndrome and Ehlers-Danlos syndrome

Sign Up to like & get
recommendations! Published in 2017 at "Scientific Reports"

DOI: 10.1038/srep46565

Abstract: Mowat-Wilson syndrome (MOWS) is a congenital disease caused by de novo heterozygous loss of function mutations or deletions of the ZEB2 gene. MOWS patients show multiple anomalies including intellectual disability, a distinctive facial appearance, microcephaly,… read more here.

Keywords: collagen; zeb2; mowat wilson; wilson syndrome ... See more keywords
Photo from wikipedia

Interaction between CASP8AP2 and ZEB2-CtBP2 Regulates the Expression of LEF1

Sign Up to like & get
recommendations! Published in 2022 at "Pediatric Hematology and Oncology"

DOI: 10.1080/08880018.2022.2033369

Abstract: Abstract Low expression of CTBP2 and CASP8AP2 correlated with poor outcome and predicted risk of relapse in pediatric B-cell acute lymphoblastic leukemia (B-ALL). This study aimed to investigate the molecular mechanism by which CASP8AP2 regulates… read more here.

Keywords: interaction; zeb2; expression; ctbp2 ... See more keywords
Photo by cdc from unsplash

MicroRNA-142-3p facilitates inflammatory response by targeting ZEB2 and activating NF-κB signaling in gouty arthritis

Sign Up to like & get
recommendations! Published in 2022 at "Cell Cycle"

DOI: 10.1080/15384101.2022.2031678

Abstract: ABSTRACT Gouty arthritis (GA) is caused by monosodium urate (MSU) crystal accumulation in the joints. MSU-mediated inflammation is an important inducing factor in gouty arthritis (GA). Recent studies have demonstrated that microRNAs can influence GA… read more here.

Keywords: mirna 142; inflammatory response; zeb2; gouty arthritis ... See more keywords
Photo by ospanali from unsplash

Long non-coding RNA HOTAIRM1 promotes proliferation and inhibits apoptosis of glioma cells by regulating the miR-873-5p/ZEB2 axis

Sign Up to like & get
recommendations! Published in 2020 at "Chinese Medical Journal"

DOI: 10.1097/cm9.0000000000000615

Abstract: Abstract Background Glioblastoma is one of the most common malignant brain tumors. Conventional clinical treatment of glioblastoma is not sufficient, and the molecular mechanism underlying the initiation and development of this disease remains unclear. Our… read more here.

Keywords: expression; mir 873; glioblastoma; zeb2 ... See more keywords
Photo by nci from unsplash

Circ_0000189 Promotes the Malignancy of Glioma Cells via Regulating miR-192-5p-ZEB2 Axis

Sign Up to like & get
recommendations! Published in 2022 at "Oxidative Medicine and Cellular Longevity"

DOI: 10.1155/2022/2521951

Abstract: Background Some recent studies have reported the role of circular RNAs (circRNAs) in modulating the tumorigenesis of human malignancies. Nevertheless, the expression characteristics, biological functions, and regulatory mechanism of circ_0000189 in glioma are unclear. Methods… read more here.

Keywords: zeb2; glioma cells; circ 0000189; mir 192 ... See more keywords
Photo by averey from unsplash

ZEB2 controls kidney stromal progenitor differentiation and inhibits abnormal myofibroblast expansion and kidney fibrosis

Sign Up to like & get
recommendations! Published in 2022 at "JCI Insight"

DOI: 10.1172/jci.insight.158418

Abstract: FOXD1+ cell–derived stromal cells give rise to pericytes and fibroblasts that support the kidney vasculature and interstitium but are also major precursors of myofibroblasts. ZEB2 is a SMAD-interacting transcription factor that is expressed in developing… read more here.

Keywords: kidney fibrosis; kidney; zeb2; stromal progenitors ... See more keywords