Functional comparison of human ACVR1 and zebrafish Acvr1l FOP‐associated variants in embryonic zebrafish
Sign Up to like & getrecommendations! Published in 2023 at "Developmental Dynamics"
DOI: 10.1002/dvdy.566
Abstract: Fibrodysplasia ossificans progressiva (FOP), a rare disease characterized by progressive heterotopic ossification of muscle and connective tissues, is caused by autosomal dominant activating mutations in the type I receptor, ACVR1/ALK2. The classic human FOP variant,… read more here.
Keywords: comparison human; zebrafish; fop; human acvr1 ... See more keywords
Cytotoxicity of lycopene‐mediated silver nanoparticles in the embryonic development of zebrafish—An animal study
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Biochemical and Molecular Toxicology"
DOI: 10.1002/jbt.23173
Abstract: Nano‐silver (AgNP) has biological properties which are significant for consumer products, food technology, and medical applications (e.g., wound care products, implantable medical devices, in diagnosis, drug delivery, and imaging). Thus, the use of nano‐silver is… read more here.
Keywords: embryonic development; silver nanoparticles; lycopene mediated; zebrafish ... See more keywords
A Robust Intrinsically Green Fluorescent Poly(Amidoamine) Dendrimer for Imaging and Traceable Central Nervous System Delivery in Zebrafish.
Sign Up to like & getrecommendations! Published in 2020 at "Small"
DOI: 10.1002/smll.202003654
Abstract: Intrinsically fluorescent poly(amidoamine) dendrimers (IF-PAMAM) are an emerging class of versatile nanoplatforms for in vitro tracking and bio-imaging. However, limited tissue penetration of their fluorescence and interference due to auto-fluorescence arising from biological tissues limit… read more here.
Keywords: traceable central; fluorescent poly; delivery; zebrafish ... See more keywords
Shedding new light on early sex determination in zebrafish
Sign Up to like & getrecommendations! Published in 2020 at "Archives of Toxicology"
DOI: 10.1007/s00204-020-02915-y
Abstract: In contrast to established zebrafish gene annotations, the question of sex determination has still not been conclusively clarified for developing zebrafish, Danio rerio, larvae, 28 dpf or earlier. Recent studies indicate polygenic sex determination (PSD),… read more here.
Keywords: p450 family; zebrafish; sex determination; sex ... See more keywords
Thiophanate-methyl induces severe hepatotoxicity in zebrafish.
Sign Up to like & getrecommendations! Published in 2020 at "Chemosphere"
DOI: 10.1016/j.chemosphere.2020.125941
Abstract: Thiophanate-methyl (TM) is widely used all over the world and is a typical example of pesticide residues, which can be detected in the soil, and even in vegetables and fruits. However, the molecular mechanisms underlying… read more here.
Keywords: zebrafish; hepatotoxicity; thiophanate methyl; methyl induces ... See more keywords
Progressive impairment of learning and memory in adult zebrafish treated by Al2O3 nanoparticles when in embryos.
Sign Up to like & getrecommendations! Published in 2020 at "Chemosphere"
DOI: 10.1016/j.chemosphere.2020.126608
Abstract: Al2O3 Nanoparticles (Al2O3-NPs) have been widely used because of their unique physical and chemical properties, and Al2O3-NPs can be released into the environment directly or indirectly. Our previous research found that 13 nm Al2O3-NPs can induce… read more here.
Keywords: adult; al2o3 nps; zebrafish; learning memory ... See more keywords
Characterization of the zebrafish orthologues of human extracellular superoxide dismutase
Sign Up to like & getrecommendations! Published in 2018 at "Free Radical Biology and Medicine"
DOI: 10.1016/j.freeradbiomed.2018.10.257
Abstract: Extracellular superoxide dismutase (SOD3) converts extracellular superoxide (O2-) into hydrogen peroxide (H2O2): a key mediator of redox signaling. Redox signaling affects diverse biological processes such as transcription, cell-cell communication, and inflammation. With respect to characterizing… read more here.
Keywords: zebrafish; extracellular superoxide; inflammatory response; zebrafish orthologues ... See more keywords
Developmental toxicity of fipronil in early development of zebrafish (Danio rerio) larvae: Disrupted vascular formation with angiogenic failure and inhibited neurogenesis.
Sign Up to like & getrecommendations! Published in 2019 at "Journal of hazardous materials"
DOI: 10.1016/j.jhazmat.2019.121531
Abstract: Fipronil has been widely used in agriculture to prevent aggressive insects from damaging agricultural products. Fipronil residues circulate in the environment and they have been detected in non-targeted organisms in aquatic environments. To study the… read more here.
Keywords: neurogenesis; zebrafish; toxicity fipronil; zebrafish embryos ... See more keywords
The Use of Tocofersolan as a Rescue Agent in Larval Zebrafish Exposed to Benzo[a]pyrene in Early Development.
Sign Up to like & getrecommendations! Published in 2021 at "Neurotoxicology"
DOI: 10.1016/j.neuro.2021.07.003
Abstract: Polycyclic aromatic hydrocarbons (PAHs) are widespread environmental pollutants created by incomplete combustion. Benzo(a)pyrene (BaP), the prototypic PAH, is known to exert toxicity through oxidative stress which is thought to occur through inhibition of antioxidant scavenging… read more here.
Keywords: early development; locomotor; zebrafish; benzo pyrene ... See more keywords
Metabolomic assessment of arsenite toxicity and novel biomarker discovery in early development of zebrafish embryos.
Sign Up to like & getrecommendations! Published in 2018 at "Toxicology letters"
DOI: 10.1016/j.toxlet.2018.03.014
Abstract: CONTEXT Arsenic poisoning commonly occurs through exposure to water contaminated with arsenic and causes long-term symptoms. Of all the arsenic derivatives, arsenite is the one of the most toxic compounds. However, the toxicity of arsenite… read more here.
Keywords: embryonic zebrafish; toxicity novel; metabolomic assessment; zebrafish ... See more keywords
Albumin uptake and distribution in the zebrafish liver as observed via correlative imaging
Sign Up to like & getrecommendations! Published in 2019 at "Experimental Cell Research"
DOI: 10.1016/j.yexcr.2018.11.020
Abstract: ABSTRACT Although liver transport routes have been extensively studied in rodents, live imaging under in situ and in vivo conditions of large volumes is still proven to be difficult. In this study, we took advantage… read more here.
Keywords: zebrafish; transport; zebrafish liver; correlative imaging ... See more keywords