Zebrafish Embryos Allow Prediction of Nanoparticle Circulation Times in Mice and Facilitate Quantification of Nanoparticle-Cell Interactions.
Sign Up to like & getrecommendations! Published in 2020 at "Small"
DOI: 10.1002/smll.201906719
Abstract: The zebrafish embryo is a vertebrate well suited for visualizing nanoparticles at high resolution in live animals. Its optical transparency and genetic versatility allow noninvasive, real-time observations of vascular flow of nanoparticles and their interactions… read more here.
Keywords: circulation times; zebrafish embryo; nanoparticle; zebrafish embryos ... See more keywords
Glyoxal Fixation as an Alternative for Zebrafish Embryo Immunostaining.
Sign Up to like & getrecommendations! Published in 2021 at "Methods in molecular biology"
DOI: 10.1007/978-1-0716-0970-5_19
Abstract: Immunohistochemistry has been widely used as a robust technique to determine the cellular and subcellular localization of proteins. This information ultimately helps to understand the function of these proteins and how biological processes are regulated.… read more here.
Keywords: fixation alternative; fixation; zebrafish embryo; alternative zebrafish ... See more keywords
Effective processing and evaluation of chemical imaging data with respect to morphological features of the zebrafish embryo
Sign Up to like & getrecommendations! Published in 2021 at "Analytical and Bioanalytical Chemistry"
DOI: 10.1007/s00216-020-03131-4
Abstract: A workflow was developed and implemented in a software tool for the automated combination of spatially resolved laser ablation-inductively coupled plasma-mass spectrometry (LA-ICP-MS) data and data on the morphology of the biological tissue. Making use… read more here.
Keywords: icp data; chemical imaging; zebrafish embryo; processing evaluation ... See more keywords
Place-based screening of mixtures of dominant emerging contaminants measured in Lake Michigan using zebrafish embryo gene expression assay.
Sign Up to like & getrecommendations! Published in 2018 at "Chemosphere"
DOI: 10.1016/j.chemosphere.2017.11.043
Abstract: Determining impacts of emerging contaminants is difficult due to the different concentrations of mixtures of these chemicals over a landscape. Assessment approaches need to account for absorption, distribution, metabolism and excretion of the chemicals in… read more here.
Keywords: lake michigan; measured lake; emerging contaminants; zebrafish embryo ... See more keywords
Exposure to prothioconazole induces developmental toxicity and cardiovascular effects on zebrafish embryo.
Sign Up to like & getrecommendations! Published in 2020 at "Chemosphere"
DOI: 10.1016/j.chemosphere.2020.126418
Abstract: Prothioconazole is a fungicide that has been widely used in general agriculture and livestock husbandry. This study evaluated the acute toxicity of prothioconazole to zebrafish embryos by assessing their hatching rate and malformation when exposed… read more here.
Keywords: zebrafish embryo; exposure; toxicity; rate ... See more keywords
Lipidomics reveals multiple stressor effects (temperature × mitochondrial toxicant) in the zebrafish embryo toxicity test.
Sign Up to like & getrecommendations! Published in 2020 at "Chemosphere"
DOI: 10.1016/j.chemosphere.2020.128472
Abstract: Aquatic organisms are exposed to multiple stressors in the environment, including contaminants and rising temperatures due to climate change. The objective of this study was to characterize the effect of increased temperature on chemical-induced toxicity… read more here.
Keywords: multiple stressor; temperature; zebrafish embryo; toxicity ... See more keywords
Promoting zebrafish embryo tool to identify the effects of chemicals in the context of Water Framework Directive monitoring and assessment
Sign Up to like & getrecommendations! Published in 2019 at "Microchemical Journal"
DOI: 10.1016/j.microc.2019.104035
Abstract: Abstract The Water Framework Directive (WFD) addresses the European Union Member States to achieve a good status of all water bodies. The WFD measures have allowed to reduce and eliminate the discharges, releases, and emissions… read more here.
Keywords: framework directive; water; monitoring; water framework ... See more keywords
Development a high-throughput zebrafish embryo acute toxicity testing method based on OECD TG 236
Sign Up to like & getrecommendations! Published in 2022 at "Toxicology Mechanisms and Methods"
DOI: 10.1080/15376516.2022.2099772
Abstract: Abstract The Organization for Economic Co-operation and Development (OECD）Test Guideline (TG) 236 for zebrafish embryo acute toxicity testing was adopted for chemical toxicity assessment in 2013. Due to the increasing demand for prediction and evaluation… read more here.
Keywords: zebrafish embryo; toxicity testing; toxicity; acute toxicity ... See more keywords
On-Chip Automatic Trapping and Rotating for Zebrafish Embryo Injection
Sign Up to like & getrecommendations! Published in 2022 at "IEEE Robotics and Automation Letters"
DOI: 10.1109/lra.2022.3194959
Abstract: Zebrafish embryo injection is often required in biomedical research using zebrafish. In the injecting operation, trapping and rotating the zebrafish embryo to achieve a proper posture is essential for the high success rate. We proposed… read more here.
Keywords: zebrafish embryo; trapping rotating; embryo injection; embryo ... See more keywords
Zebrafish Embryo Model for Assessment of Drug Efficacy on Mycobacterial Persisters
Sign Up to like & getrecommendations! Published in 2020 at "Antimicrobial Agents and Chemotherapy"
DOI: 10.1128/aac.00801-20
Abstract: Tuberculosis continues to kill millions of people each year. The main difficulty in eradication of the disease is the prolonged duration of treatment, which takes at least 6 months. Persister cells have long been associated with… read more here.
Keywords: persister; drug; treatment; vivo ... See more keywords
Knockdown of Laminin gamma-3 (Lamc3) impairs motoneuron guidance in the zebrafish embryo
Sign Up to like & getrecommendations! Published in 2017 at "Wellcome Open Research"
DOI: 10.12688/wellcomeopenres.12394.1
Abstract: Background: Previous work in the zebrafish embryo has shown that laminin γ-3 ( lamc3) is enriched in endothelial cells marked by expression of fli1a, but the role of Lamc3 has been unknown. Methods: We use… read more here.
Keywords: zebrafish embryo; motoneuron guidance; guidance; expression ... See more keywords