Zebrafish sirt7 Negatively Regulates Antiviral Responses by Attenuating Phosphorylation of irf3 and irf7 Independent of Its Enzymatic Activity.
Sign Up to like & getrecommendations! Published in 2021 at "Journal of immunology"
DOI: 10.4049/jimmunol.2100318
Abstract: Sirt7 is one member of the sirtuin family proteins with NAD (NAD+)-dependent histone deacetylase activity. In this study, we report that zebrafish sirt7 is induced upon viral infection, and overexpression of sirt7 suppresses cellular antiviral… read more here.
Keywords: zebrafish sirt7; activity; sirt7; phosphorylation irf3 ... See more keywords