Zerumbone Induces Apoptosis in Non‐Small‐Cell Lung Cancer via Biomolecular Alterations: A Microscopic and Spectroscopic Study
Sign Up to like & getrecommendations! Published in 2025 at "Journal of Biophotonics"
DOI: 10.1002/jbio.202400500
Abstract: Zerumbone is a sesquiterpene phytochemical with cytotoxic activity against cancer. This study aimed to evaluate the effect of zerumbone on cell viability by WST‐1 test, apoptosis by TUNEL, lipid peroxidation markers (malondialdehyde, MDA, and 4‐hydroxynonenal,… read more here.
Keywords: cancer; cell; zerumbone; zerumbone treated ... See more keywords
Zerumbone protects human skin keratinocytes against UVA‐irradiated damages through Nrf2 induction
Sign Up to like & getrecommendations! Published in 2018 at "Biochemical Pharmacology"
DOI: 10.1016/j.bcp.2017.12.014
Abstract: Graphical abstract Figure. No caption available. ABSTRACT Ultraviolet A (UVA) irradiation is toxic to skin as it penetrates deep into the dermis and damages cellular components through excessive reactive oxygen species (ROS) production, which accelerates… read more here.
Keywords: skin; human skin; uva irradiated; zerumbone mediated ... See more keywords
Zingiber zerumbet (L.) Roscoe ex Sm. from northern India: Potential source of zerumbone rich essential oil for antiproliferative and antibacterial applications
Sign Up to like & getrecommendations! Published in 2018 at "Industrial Crops and Products"
DOI: 10.1016/j.indcrop.2018.01.006
Abstract: Abstract Zingiber zerumbet (L.) Roscoe ex Sm. (Zingiberaceae), commonly known as bitter ginger, has long been used in traditional herbal medicine for the treatments of inflammations, rheumatism, sprains, colic pain, diarrhea, tonsillitis and various other… read more here.
Keywords: essential oil; zingiber zerumbet; zerumbet roscoe; zerumbone ... See more keywords
Protective effect of zerumbone reduces lipopolysaccharide‐induced acute lung injury via antioxidative enzymes and Nrf2/HO‐1 pathway
Sign Up to like & getrecommendations! Published in 2017 at "International Immunopharmacology"
DOI: 10.1016/j.intimp.2017.03.008
Abstract: Abstract Acute lung injury (ALI) is a serious disease with high morbidity and mortality rate. Although there are effective strategies for treatment of ALI; a widely accepted specific pharmacotherapy has not yet established. Zerumbone, the… read more here.
Keywords: induced ali; lps induced; acute lung; zerumbone ... See more keywords
Healing potential of zerumbone ointment on experimental full-thickness excision cutaneous wounds in rat.
Sign Up to like & getrecommendations! Published in 2017 at "Journal of tissue viability"
DOI: 10.1016/j.jtv.2017.04.002
Abstract: Zerumbone is a monocyclic sesquiterpene compound. Based on report, it is the predominant bioactive compound from the rhizomes of Zingiber zerumbet. The study was undertaken to evaluate the therapeutic effects of topical zerumbone on excision… read more here.
Keywords: full thickness; excision; zerumbone ointment; zerumbone ... See more keywords
Kalparinol, a Salvialane (Isodaucane) Sesquiterpenoid Derived from Native Australian Dysphania Species That Suggests a Putative Biogenetic Link to Zerumbone.
Sign Up to like & getrecommendations! Published in 2020 at "Journal of natural products"
DOI: 10.1021/acs.jnatprod.9b01039
Abstract: Dysphania is a genus of plants endemic to the Australian continent, occurring primarily in arid and temperate zones. Despite their prevalence, very little in the way of phytochemical and/or bioactivity investigation of native Dysphania has… read more here.
Keywords: dysphania; kalparinol salvialane; isodaucane sesquiterpenoid; isodaucane ... See more keywords
Accessing Polycyclic Terpenoids from Zerumbone via Lewis Acid Catalyzed Synthetic Strategies
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DOI: 10.1055/s-0039-1690840
Abstract: We herein disclose an effective strategy for the synthesis of [5.3.0] and [6.3.0] fused polycyclic terpenoids, which are important structural elements of natural products and biologically active compounds. The method comprises of Lewis acid catalyzed… read more here.
Keywords: lewis acid; terpenoids zerumbone; accessing polycyclic; polycyclic terpenoids ... See more keywords
Editor's Note: Zerumbone Enhances TRAIL-Induced Apoptosis through the Induction of Death Receptors in Human Colon Cancer Cells: Evidence for an Essential Role of Reactive Oxygen Species.
Sign Up to like & getrecommendations! Published in 2018 at "Cancer research"
DOI: 10.1158/0008-5472.can-18-1828
Abstract: The editors are publishing this note to alert readers to a concern about this article (1). It appears that the same image was used to represent the effects of DR5 siRNA in cells cultured in… read more here.
Keywords: zerumbone enhances; note zerumbone; editor note; enhances trail ... See more keywords
Evaluation of anti-methicillin-resistant Staphylococcus aureus property of zerumbone.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of applied biomedicine"
DOI: 10.32725/jab.2022.002
Abstract: CONTEXT AND OBJECTIVE Zerumbone has been reported to exert anti-microbial effects, but the mechanism by which the compound exerts its action is not known. Thus, this study aimed to investigate the mechanism of action of… read more here.
Keywords: methicillin; microscopy; staphylococcus aureus; zerumbone ... See more keywords
Zerumbone Inhibits Helicobacter pylori Urease Activity
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DOI: 10.3390/molecules26092663
Abstract: Helicobacter pylori (H. pylori) produces urease in order to improve its settlement and growth in the human gastric epithelium. Urease inhibitors likely represent potentially powerful therapeutics for treating H. pylori; however, their instability and toxicity… read more here.
Keywords: zerumbone; urease activity; urease; pylori urease ... See more keywords
Zerumbone Ameliorates Neuropathic Pain Symptoms via Cannabinoid and PPAR Receptors Using In Vivo and In Silico Models
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DOI: 10.3390/molecules26133849
Abstract: Neuropathic pain is a chronic pain condition persisting past the presence of any noxious stimulus or inflammation. Zerumbone, of the Zingiber zerumbet ginger plant, has exhibited anti-allodynic and antihyperalgesic effects in a neuropathic pain animal… read more here.
Keywords: ppar; neuropathic pain; receptor; zerumbone ... See more keywords