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Zetomipzomib (KZR-616) attenuates lupus in mice via modulation of innate and adaptive immune responses

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Published in 2023 at "Frontiers in Immunology"

DOI: 10.3389/fimmu.2023.1043680

Abstract: Zetomipzomib (KZR-616) is a selective inhibitor of the immunoproteasome currently undergoing clinical investigation in autoimmune disorders. Here, we characterized KZR-616 in vitro and in vivo using multiplexed cytokine analysis, lymphocyte activation and differentiation, and differential… read more here.

Keywords: 616 attenuates; mice via; kzr 616; zetomipzomib kzr ... See more keywords