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   Articles with "zfas1" as a keyword



IncRNA‐ZFAS1, an Emerging Gate‐Keeper in DNA Damage‐Dependent Transcriptional Regulation

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recommendations! Published in 2025 at "Advanced Science"

DOI: 10.1002/advs.202412385

Abstract: Numerous long noncoding RNAs (lncRNAs) are generated in response to external stimuli, but the scope and functions of such activity are not known. Here, this study provides insight into how the transcription of lncRNAs is… read more here.

Keywords: dna damage; zfas1; damage; regulation ... See more keywords

The role of blood lnc‐ZFAS1 in acute ischemic stroke: correlation with neurological impairment, inflammation, and survival profiles

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recommendations! Published in 2021 at "Journal of Clinical Laboratory Analysis"

DOI: 10.1002/jcla.24219

Abstract: Long non‐coding RNA zinc finger antisense 1 (lnc‐ZFAS1) has been reported to inhibit neuronal damage in acute ischemic stroke (AIS). However, the role of lnc‐ZFAS1 in AIS patients remains unclear. Therefore, we assessed the relationship… read more here.

Keywords: zfas1; neurological impairment; acute ischemic; lnc zfas1 ... See more keywords

ZNFX1 antisense RNA1 promotes antiviral innate immune responses via modulating ZNFX1 function

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recommendations! Published in 2023 at "Journal of Medical Virology"

DOI: 10.1002/jmv.28637

Abstract: Increasing evidence suggests that natural antisense transcriptional lncRNAs regulate their adjacent coding genes to mediate diverse aspects of biology. Bioinformatics analysis of the previously identified antiviral gene ZNFX1 revealed neighboring lncRNA ZFAS1 transcribed on the… read more here.

Keywords: zfas1; function; znfx1; antiviral innate ... See more keywords

LncRNA ZFAS1 promotes laryngeal cancer progression through RBFOX2‐mediated MENA alternative splicing

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recommendations! Published in 2022 at "Environmental Toxicology"

DOI: 10.1002/tox.23695

Abstract: Laryngeal cancer (LC) is the most common aggressive malignancy of the head and neck. LncRNA ZNFX1 antisense RNA 1 (ZFAS1) displays oncogenic properties in head and neck squamous cell carcinoma, but its regulatory role in… read more here.

Keywords: zfas1; rbfox2; laryngeal cancer; cancer progression ... See more keywords

LncRNA ZFAS1 regulates ATIC transcription and promotes the proliferation and migration of hepatocellular carcinoma through the PI3K/AKT signaling pathway

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recommendations! Published in 2024 at "Journal of Cancer Research and Clinical Oncology"

DOI: 10.1007/s00432-024-05877-1

Abstract: Long noncoding RNAs (lncRNAs) exert a significant influence on various cancer-related processes through their intricate interactions with RNAs. Among these, lncRNA ZFAS1 has been implicated in oncogenic roles in multiple cancer types. Nevertheless, the intricate… read more here.

Keywords: zfas1 atic; zfas1; lncrna zfas1; proliferation migration ... See more keywords
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Long non-coding RNA ZFAS1 promotes the expression of EPAS1 in gastric cardia adenocarcinoma

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recommendations! Published in 2021 at "Journal of Advanced Research"

DOI: 10.1016/j.jare.2020.06.006

Abstract: Graphical abstract The hypoxia microenvironment induces the expression of HIF1 and EPAS1 in GCA. During tumor development, the EPAS1 suppresses the expression of HIF1, resulting in the dominant form of HIFs switching from HIF1 to… read more here.

Keywords: long non; non coding; hif1 epas1; coding rna ... See more keywords

Long non-coding RNA ZFAS1 regulates cell proliferation and invasion in cervical cancer via the miR-190a-3p/KLF6 axis

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recommendations! Published in 2022 at "Bioengineered"

DOI: 10.1080/21655979.2021.2022265

Abstract: ABSTRACT Long non-coding RNA (lncRNA) ZFAS1 (zinc finger antisense 1) was demonstrated to play critical roles in various cancer progression. However, the functions of ZFAS in cervical cancers (CC) are unclear. Human CC cell lines… read more here.

Keywords: zfas1; tumor; 190a klf6; expression ... See more keywords

Long non-coding RNA ZNFX1 antisense 1 (ZFAS1) suppresses anti-oxidative stress in chondrocytes during osteoarthritis by sponging microRNA-1323

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recommendations! Published in 2022 at "Bioengineered"

DOI: 10.1080/21655979.2022.2074770

Abstract: ABSTRACT LncRNAs play a regulatory role in osteoarthritis (OA); however, the detailed mechanism remains to be elucidated. This study aimed to investigate the role of lncRNA zinc finger NFX1-type containing 1 (ZNFX1) antisense 1 (ZFAS1)… read more here.

Keywords: zfas1; oxidative stress; antisense zfas1; anti oxidative ... See more keywords

Resveratrol regulates PINK1/Parkin-mediated mitophagy via the lncRNA ZFAS1-miR-150-5p-PINK1 axis, and enhances the antitumor activity of paclitaxel against non-small cell lung cancer.

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recommendations! Published in 2022 at "Toxicology research"

DOI: 10.1093/toxres/tfac072

Abstract: Non-small cell lung cancer (NSCLC) is a common malignant subtype of lung cancer with high mortality. Resveratrol (RSV) is a natural molecule that regulates mitochondrial metabolism. Here, we explored the effect of RSV on NSCLC… read more here.

Keywords: lung cancer; zfas1; zfas1 mir; pink1 ... See more keywords

Inhibition of the long non-coding RNA ZFAS1 attenuates ferroptosis by sponging miR-150-5p and activates CCND2 against diabetic cardiomyopathy.

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recommendations! Published in 2021 at "Journal of cellular and molecular medicine"

DOI: 10.1111/jcmm.16890

Abstract: Diabetic cardiomyopathy (DbCM) is responsible for increased morbidity and mortality in patients with diabetes and heart failure. However, the pathogenesis of DbCM has not yet been identified. Here, we investigated the important role of lncRNA-ZFAS1… read more here.

Keywords: ccnd2; dbcm; inhibition; ferroptosis ... See more keywords

lncRNA ZFAS1 Positively Facilitates Endothelial Ferroptosis via miR-7-5p/ACSL4 Axis in Diabetic Retinopathy

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recommendations! Published in 2022 at "Oxidative Medicine and Cellular Longevity"

DOI: 10.1155/2022/9004738

Abstract: Accumulating evidence has suggested the significant role of long noncoding RNAs (lncRNA) in regulating ferroptosis, while its regulatory mechanism in diabetic retinopathy (DR) remains unelucidated. In this work, we first demonstrated that lncRNA zinc finger… read more here.

Keywords: acsl4 axis; zfas1; mir acsl4; diabetic retinopathy ... See more keywords