Association of ZFHX3 gene variation with atrial fibrillation, cerebral infarction, and lung thromboembolism: An autopsy study.
Sign Up to like & getrecommendations! Published in 2017 at "Journal of cardiology"
DOI: 10.1016/j.jjcc.2016.11.005
Abstract: AIM We aimed to study a single nucleotide polymorphism (SNP), rs2106261, in the transcription factor gene, ZFHX3, in atrial fibrillation (AF) and other related phenotypes by phenome scanning in a Japanese population. METHOD We retrieved… read more here.
Keywords: atrial fibrillation; rs2106261; study; gene ... See more keywords
Abstract 6716: Effect of ZFHX3 in endometrial cancer progression
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DOI: 10.1158/1538-7445.am2025-6716
Abstract: Endometrial cancer (EC) is the most prevalent gynecological cancer and the 4th most common cancer in women globally. The frequency of EC is increasing in contrast to other prevalent cancers driven by lifestyle choices and… read more here.
Keywords: zfhx3; cancer; zfhx3 endometrial; endometrial cancer ... See more keywords
Myeloid Zfhx3 deficiency protects against hypercapnia-induced suppression of host defense against influenza A virus
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DOI: 10.1172/jci.insight.170316
Abstract: Hypercapnia, elevation of the partial pressure of CO2 in blood and tissues, is a risk factor for mortality in patients with severe acute and chronic lung diseases. We previously showed that hypercapnia inhibits multiple macrophage… read more here.
Keywords: zfhx3; myeloid zfhx3; influenza virus; hypercapnia ... See more keywords
Association study between ZFHX3 gene polymorphisms and obesity in Korean population
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Exercise Rehabilitation"
DOI: 10.12965/jer.1735080.540
Abstract: The aim of this study is to investigate whether single nucleotide polymorphisms (SNPs) of zinc finger homeobox 3 (ZFHX3 ) gene are susceptibility to obesity. Recently, several study suggested that specific polymorphisms in various genes… read more here.
Keywords: snps zfhx3; study; association; zfhx3 gene ... See more keywords
Association of ZFHX3 Genetic Polymorphisms and Extra-Pulmonary Vein Triggers in Patients With Atrial Fibrillation Who Underwent Catheter Ablation
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DOI: 10.3389/fphys.2021.807545
Abstract: Background: The ZFHX3 gene (16q22) is the second most highly associated gene with atrial fibrillation (AF) and is related to inflammation and fibrosis. We hypothesized that ZFHX3 is associated with extra-pulmonary vein (PV) triggers, left… read more here.
Keywords: extra triggers; zfhx3; pulmonary vein; model ... See more keywords
Zfhx3 Transcription Factor Represses the Expression of SCN5A Gene and Decreases Sodium Current Density (INa)
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DOI: 10.3390/ijms222313031
Abstract: The ZFHX3 and SCN5A genes encode the zinc finger homeobox 3 (Zfhx3) transcription factor (TF) and the human cardiac Na+ channel (Nav1.5), respectively. The effects of Zfhx3 on the expression of the Nav1.5 channel, and… read more here.
Keywords: expression; density; zfhx3; zfhx3 transcription ... See more keywords