A novel homozygous variant in ZFP36L2 cause female infertility due to oocyte maturation defect.
Sign Up to like & getrecommendations! Published in 2023 at "Clinical genetics"
DOI: 10.1111/cge.14362
Abstract: Normal oocyte maturation is an important requirement for the success of human reproduction, and defects in this process will lead to female infertility and repeated IVF/ICSI failures. In order to identify genetic factors that are… read more here.
Keywords: maturation; maturation defect; oocyte maturation; female infertility ... See more keywords
High expression of ZFP36L2 correlates with the prognosis and immune infiltration in lower-grade glioma
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Genetics"
DOI: 10.3389/fgene.2022.914219
Abstract: Background: The ZFP36 Ring Finger Protein Like 2 (ZFP36L2) is an RNA-binding protein that regulates gene expression at post-transcriptional level. However, the clinical significance and prognostic value of ZFP36L2 in lower-grade glioma (LGG) remain unclear.… read more here.
Keywords: immune infiltration; grade glioma; expression; zfp36l2 ... See more keywords
ZFP36L2 Role in Thyroid Functionality
Sign Up to like & getrecommendations! Published in 2021 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms22179379
Abstract: Thyroid hormone levels are usually genetically determined. Thyrocytes produce a unique set of enzymes that are dedicated to thyroid hormone synthesis. While thyroid transcriptional regulation is well-characterized, post-transcriptional mechanisms have been less investigated. Here, we… read more here.
Keywords: role thyroid; zfp36l2 role; thyroid functionality; thyroid specific ... See more keywords