ZFR promotes cell proliferation and tumor development in colorectal and liver cancers.
Sign Up to like & getrecommendations! Published in 2019 at "Biochemical and biophysical research communications"
DOI: 10.1016/j.bbrc.2019.04.103
Abstract: Colorectal cancer (CRC) and liver cancer are the second and fourth leading causes of cancer-related deaths in the whole world, respectively, and each year over 1.6 million people die from these diseases. To identify driver… read more here.
Keywords: cancer; zfr; tumor development; liver ... See more keywords
ZFR coordinates crosstalk between RNA decay and transcription in innate immunity
Sign Up to like & getrecommendations! Published in 2018 at "Nature Communications"
DOI: 10.1038/s41467-018-03326-5
Abstract: Control of type I interferon production is crucial to combat infection while preventing deleterious inflammatory responses, but the extent of the contribution of post-transcriptional mechanisms to innate immune regulation is unclear. Here, we show that… read more here.
Keywords: innate; zfr; decay; type interferon ... See more keywords
CircRNA ZFR stimulates the proliferation of hepatocellular carcinoma through upregulating MAP2K1.
Sign Up to like & getrecommendations! Published in 2020 at "European review for medical and pharmacological sciences"
DOI: 10.26355/eurrev_202010_23203
Abstract: OBJECTIVE The aim of the study was to illustrate the function of circRNA ZFR in aggravating the development of hepatocellular carcinoma (HCC) by upregulating MAP2K1. PATIENTS AND METHODS CircRNA ZFR levels in 62 paired HCC… read more here.
Keywords: hepatocellular carcinoma; zfr; hcc; upregulating map2k1 ... See more keywords