Ependymoma associated protein Zfta is expressed in immature ependymal cells but is not essential for ependymal development in mice
Sign Up to like & getrecommendations! Published in 2022 at "Scientific Reports"
DOI: 10.1038/s41598-022-05526-y
Abstract: The fusion protein of uncharacterised zinc finger translocation associated (ZFTA) and effector transcription factor of tumorigenic NF-κB signalling, RELA (ZFTA-RELA), is expressed in more than two-thirds of supratentorial ependymoma (ST-EPN-RELA), but ZFTA’s expression profile and… read more here.
Keywords: zfta; zfta rela; expression; ependymal cells ... See more keywords
ZFTA-translocations constitute ependymoma chromatin remodeling and transcription factors.
Sign Up to like & getrecommendations! Published in 2021 at "Cancer discovery"
DOI: 10.1158/2159-8290.cd-20-1052
Abstract: ZFTA (C11orf95)-a gene of unknown function-partners with a variety of transcriptional co-activators in translocations that drive supratentorial ependymoma, a frequently lethal brain tumor. Understanding the function of ZFTA is key to developing therapies that inhibit… read more here.
Keywords: chromatin; zfta; translocations constitute; fusion proteins ... See more keywords