Articles with "zfx" as a keyword



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LncRNA NFIA-AS2 promotes glioma progression through modulating the miR-655-3p/ZFX axis

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Published in 2020 at "Human Cell"

DOI: 10.1007/s13577-020-00408-9

Abstract: Long non-coding RNAs (lncRNAs) are closely associated with tumorigenesis of various malignancies, including glioma. However, the roles of most lncRNAs in glioma remain undiscovered. The present study for the first time explored the roles of… read more here.

Keywords: zfx; mir 655; glioma; nfia as2 ... See more keywords
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ZFX promotes tumorigenesis and confers chemotherapy resistance in esophageal squamous cell carcinoma.

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Published in 2021 at "Clinics and research in hepatology and gastroenterology"

DOI: 10.1016/j.clinre.2020.101586

Abstract: INTRODUCTION Zinc finger X-chromosomal protein (ZFX) has been shown to be essential for the development and progression of multiple types of human cancers. However, its potential roles in esophageal squamous cell carcinoma (ESCC) have not… read more here.

Keywords: esophageal squamous; cell carcinoma; squamous cell; zfx ... See more keywords
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ZFX Mediates Non-canonical Oncogenic Functions of the Androgen Receptor Splice Variant 7 in Castrate-Resistant Prostate Cancer.

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Published in 2018 at "Molecular cell"

DOI: 10.1016/j.molcel.2018.08.029

Abstract: Androgen receptor splice variant 7 (AR-V7) is crucial for prostate cancer progression and therapeutic resistance. We show that, independent of ligand, AR-V7 binds both androgen-responsive elements (AREs) and non-canonical sites distinct from full-length AR (AR-FL)… read more here.

Keywords: prostate; zfx; prostate cancer; non canonical ... See more keywords
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Zinc Finger Protein X-Linked Exhibits Pro-Leukemia Activity Via WNT3 in Chronic Myeloid Leukemia Stem/Progenitor Cells

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Published in 2018 at "Blood"

DOI: 10.1182/blood-2018-99-114663

Abstract: Zinc Finger protein, X-linked (ZFX) is a transcriptional regulator, which controls the self-renewal of both embryonic and hematopoietic stem cells and participates in pathogenesis of various cancers. Zfx deficiency impairs Notch intracellular domain (NotchIC) induced… read more here.

Keywords: wnt3; zfx; stem progenitor; stem ... See more keywords