The ZGRF1 Helicase Promotes Recombinational Repair of Replication-Blocking DNA Damage in Human Cells
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DOI: 10.1016/j.celrep.2020.107849
Abstract: SUMMARY Replication-blocking DNA lesions are particularly toxic to proliferating cells because they can lead to chromosome mis-segregation if not repaired prior to mitosis. In this study, we report that ZGRF1 null cells accumulate chromosome aberrations… read more here.
Keywords: dna damage; repair replication; replication blocking; zgrf1 helicase ... See more keywords