Tumor suppressor ZHX2 restricts hepatitis B virus replication via epigenetic and non‐epigenetic manners
Sign Up to like & getrecommendations! Published in 2018 at "Antiviral Research"
DOI: 10.1016/j.antiviral.2018.03.008
Abstract: &NA; Hepatitis B virus (HBV) covalently closed circular DNA (cccDNA), the stable genomic form as the template for viral transcription, plays a crucial role in viral persistence which remains a major global health problem. While… read more here.
Keywords: transcription; cccdna; hbv; zhx2 ... See more keywords
Tumor suppressor ZHX2 inhibits NAFLD–HCC progression via blocking LPL-mediated lipid uptake
Sign Up to like & getrecommendations! Published in 2019 at "Cell Death and Differentiation"
DOI: 10.1038/s41418-019-0453-z
Abstract: Non-alcoholic fatty liver disease (NAFLD) leads to hepatocellular carcinoma (HCC). However, the underlying mechanism remains largely unclear. Here, we investigated the role of the tumor suppressor Zinc fingers and homeoboxes 2 (ZHX2) in the progression… read more here.
Keywords: hcc; lpl; zhx2; progression ... See more keywords
Cytokine storm based mechanisms for extra-pulmonary manifestations of SARS-CoV-2 infection.
Sign Up to like & getrecommendations! Published in 2023 at "JCI insight"
DOI: 10.1172/jci.insight.166012
Abstract: Viral illnesses like SARS-CoV-2 have pathologic effects on non-respiratory organs in the absence of direct viral infection. We injected mice with cocktails of rodent equivalents of human cytokine storms resulting from SARS-CoV-2 / COVID-19 or… read more here.
Keywords: cytokine; infection; zhx2 hypomorph; zhx2 ... See more keywords