Toxicological evaluation of zidovudine and novel chalcogen derivatives in Drosophila melanogaster.
Sign Up to like & getrecommendations! Published in 2023 at "Journal of biochemical and molecular toxicology"
DOI: 10.1002/jbt.23356
Abstract: Zidovudine (AZT) is the most commonly prescribed antiviral drug for the treatment of human immunodeficiency virus (HIV) infection. However, its chronic administration causes toxic side effects limiting its use. This study aimed to evaluate the… read more here.
Keywords: novel chalcogen; chalcogen derivatives; toxicity; zidovudine ... See more keywords
Reversible diabetes mellitus induced by use of, and improved after discontinuation of, the antiretroviral medication zidovudine: a case report
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DOI: 10.1186/s13256-017-1326-z
Abstract: BackgroundWith the advent of effective antiretroviral therapy, the care of patients with human immunodeficiency virus infection became more like that of other chronic diseases. Diabetes mellitus can also occur as one of the chronic illnesses… read more here.
Keywords: human immunodeficiency; case; diabetes mellitus; immunodeficiency virus ... See more keywords
Hair Zidovudine Concentrations Predict Virologic Outcomes Among People Living with HIV/AIDS in China
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DOI: 10.2147/ppa.s371623
Abstract: Background Hair antiretroviral concentrations are an objective and non-invasive measure of adherence to long-term antiretroviral therapy (ART) and can further predict virologic outcomes among people living with HIV/AIDS (PLWH). Zidovudine, one of the mainstream antiretrovirals… read more here.
Keywords: virologic suppression; predict virologic; hair zidovudine; zidovudine ... See more keywords
Quality by Design Optimization of Cold Sonochemical Synthesis of Zidovudine-Lamivudine Nanosuspensions
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DOI: 10.3390/pharmaceutics12040367
Abstract: Lamivudine (3TC) and zidovudine (AZT) are antiviral agents used to manage HIV/AIDS infection. The compounds require frequent dosing, exhibit unpredictable bioavailability and a side effect profile that includes hepato- and haema-toxicity. A novel pseudo one-solvent… read more here.
Keywords: zidovudine; nano crystals; lamivudine; spectroscopy ... See more keywords