Temperature-dependent folding allows stable dimerization of secretory and virus-associated E proteins of Dengue and Zika viruses in mammalian cells
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DOI: 10.1038/s41598-017-01097-5
Abstract: Dengue and Zika are two of the most important human viral pathogens worldwide. In both cases, the envelope glycoprotein E is the main target of the antibody response. Recently, new complex quaternary epitopes were identified… read more here.
Keywords: zika viruses; dengue zika; viruses mammalian; mammalian cells ... See more keywords
Clustering of Zika viruses originating from different geographical regions using computational sequence descriptors.
Sign Up to like & getrecommendations! Published in 2019 at "Current computer-aided drug design"
DOI: 10.2174/1573409916666191226110936
Abstract: In this report we consider a data set, which consists of 310 Zika virus genome sequences taken from different continents, Africa, Asia and South America. The sequences, which were compiled from GenBank, were derived from… read more here.
Keywords: zika viruses; genome sequences; clustering zika; zika virus ... See more keywords
Environmental Changes and the Impact on the Human Infections by Dengue, Chikungunya and Zika Viruses in Northern Brazil, 2010–2019
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DOI: 10.3390/ijerph191912665
Abstract: Environmental changes are among the main factors that contribute to the emergence or re-emergence of viruses of public health importance. Here, we show the impact of environmental modifications on cases of infections by the dengue,… read more here.
Keywords: chikungunya zika; dengue chikungunya; environmental changes; 2010 2019 ... See more keywords
Antiviral Effect of Stenocline ericoides DC. and Stenocline inuloides DC., Two Flavonoid-Rich Endemic Plants from Madagascar, against Dengue and Zika Viruses
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DOI: 10.3390/ph15121500
Abstract: Dengue and Zika viruses are identified as the most medically important arthropod-borne viral pathogens. Over the past 20 years, the global dengue incidence has dramatically increased with epidemics of severe dengue where the case fatality… read more here.
Keywords: zika viruses; dengue zika; stenocline ericoides; effect ... See more keywords
Dengue, West Nile, and Zika Viruses: Potential Novel Antiviral Biologics Drugs Currently at Discovery and Preclinical Development Stages
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DOI: 10.3390/pharmaceutics14112535
Abstract: Dengue, West Nile and Zika viruses are vector-borne flaviviruses responsible for numerous disease outbreaks in both Hemispheres. Despite relatively low mortality, infection may lead to potentially severe situations such as (depending on the virus): hypovolemic… read more here.
Keywords: nile zika; dengue west; discovery preclinical; west nile ... See more keywords