Zika virus NS1 affects the junctional integrity of human brain microvascular endothelial cells.
Sign Up to like & getrecommendations! Published in 2020 at "Biochimie"
DOI: 10.1016/j.biochi.2020.06.011
Abstract: Zika virus (ZIKV) infection leads to microcephaly in newborns. Flaviviruses are known to secrete NS1 protein extracellularly and its concentration in serum directly co-relate to disease severity. The presence of ZIKV-NS1 near the brain microvascular… read more here.
Keywords: brain microvascular; microvascular endothelial; zika virus; brain ... See more keywords
Non‐structural protein 1‐specific antibodies directed against Zika virus in humans mediate antibody‐dependent cellular cytotoxicity
Sign Up to like & getrecommendations! Published in 2021 at "Immunology"
DOI: 10.1111/imm.13380
Abstract: There is growing interest in understanding antibody (Ab) function beyond neutralization. The non‐structural protein 1 (NS1) of Zika virus (ZIKV) is an attractive candidate for an effective vaccine as Abs against NS1, unlike the envelope… read more here.
Keywords: non structural; zikv; antibody dependent; virus ... See more keywords
Detection of Anti-ZIKV NS1 IgA, IgM, and Combined IgA/IgM and Identification of IL-4 and IL-10 as Potential Biomarkers for Early ZIKV and DENV Infections in Hyperendemic Regions, Thailand
Sign Up to like & getrecommendations! Published in 2023 at "Tropical Medicine and Infectious Disease"
DOI: 10.3390/tropicalmed8050284
Abstract: The frequency of Zika virus (ZIKV)-specific IgA and IgM and the cytokine expression profile of ZIKV-infected patients in hyperendemic areas remain unclear. This study investigated the rates of ZIKV non-structural protein 1 (NS1)-specific IgA and… read more here.
Keywords: zikv denv; iga igm; ns1 iga; zikv ... See more keywords