Boroleucine‐Derived Covalent Inhibitors of the ZIKV Protease
Sign Up to like & getrecommendations! Published in 2022 at "Chemmedchem"
DOI: 10.1002/cmdc.202200336
Abstract: The Zika virus (ZIKV) remains a potential threat to the public health due to the lack of both an approved vaccination or a specific treatment. In this work, a series of peptidic inhibitors of the… read more here.
Keywords: boroleucine derived; zikv protease; boroleucine; inhibitors zikv ... See more keywords
Increased activity of unlinked Zika virus NS2B/NS3 protease compared to linked Zika virus protease.
Sign Up to like & getrecommendations! Published in 2017 at "Biochemical and biophysical research communications"
DOI: 10.1016/j.bbrc.2017.03.108
Abstract: Zika virus (ZIKV) is a flavivirus spread by daytime-active Aedes spp. mosquitoes such as A. aegypti and A. albopictus. Previously thought to be a mild infection, the latest ZIKV outbreak in the Americas is causally associated with… read more here.
Keywords: zikv protease; ns3 protease; protease; ns2b ns3 ... See more keywords