Iminosugars With Endoplasmic Reticulum α-Glucosidase Inhibitor Activity Inhibit ZIKV Replication and Reverse Cytopathogenicity in vitro
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DOI: 10.3389/fmicb.2020.00531
Abstract: Zika virus (ZIKV), a vector-borne virus of the family Flaviviridae, continues to spread and remains a significant global public health threat. Currently, there are no approved vaccines or antivirals against ZIKV. We investigated the anti-ZIKV… read more here.
Keywords: endoplasmic reticulum; zikv replication; iminosugars endoplasmic; replication ... See more keywords
Chloroquine and Sulfadoxine Derivatives Inhibit ZIKV Replication in Cervical Cells
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DOI: 10.3390/v13010036
Abstract: Despite the severe morbidity caused by Zika fever, its specific treatment is still a challenge for public health. Several research groups have investigated the drug repurposing of chloroquine. However, the highly toxic side effect induced… read more here.
Keywords: zikv replication; chloroquine sulfadoxine; cervical cells; sds ... See more keywords