Zinc Fingers, TALEs, and CRISPR Systems: A Comparison of Tools for Epigenome Editing.
Sign Up to like & getrecommendations! Published in 2018 at "Methods in molecular biology"
DOI: 10.1007/978-1-4939-7774-1_2
Abstract: The completion of genome, epigenome, and transcriptome mapping in multiple cell types has created a demand for precision biomolecular tools that allow researchers to functionally manipulate DNA, reconfigure chromatin structure, and ultimately reshape gene expression… read more here.
Keywords: fingers tales; gene expression; biology; zinc fingers ... See more keywords
Breaking the spatial constraint between neighboring zinc fingers: a new germline mutation in GATA2 deficiency syndrome
Sign Up to like & getrecommendations! Published in 2020 at "Leukemia"
DOI: 10.1038/s41375-020-0820-2
Abstract: GATA2 deficiency syndrome is an autosomal dominant disorder caused by germline mutations in the GATA2 gene, which encodes a transcription factor with two zinc fingers that is essential for hematopoiesis. There are four classes of… read more here.
Keywords: zinc fingers; gata2 deficiency; gata2; mutation ... See more keywords