Transport of Zinc‐Phthalocyanine to Cancer Cells Using Myoglobin−Albumin Fusion Protein for Photodynamic Therapy
Sign Up to like & getrecommendations! Published in 2024 at "ChemBioChem"
DOI: 10.1002/cbic.202400329
Abstract: Photodynamic therapy (PDT) is a noninvasive approach to cancer treatment, wherein cell death is initiated by singlet oxygen (1O2) production via energy transfer from excited photosensitizers to ground‐state O2. Effective clinical photosensitizers necessitate water solubility… read more here.
Keywords: cancer; cancer cells; albumin fusion; fusion protein ... See more keywords
Novel Polymer Supported Phthalocyanine Nanosensors and Analytical Application
Sign Up to like & getrecommendations! Published in 2025 at "Topics in Catalysis"
DOI: 10.1007/s11244-025-02072-5
Abstract: In this study, a novel PCL-based polymer (6) containing A3B-type zinc phthalocyanine was synthesized as a result of the ring-opening polymerization of ε-caprolactone (ε-CL), in which A3B-type zinc phthalocyanine (5) prepared by condensation method of… read more here.
Keywords: a3b type; type zinc; polymer; zinc phthalocyanine ... See more keywords
Construction of anthraquinone functional zinc phthalocyanine sensor platform for ultra-trace amount of water determination in tetrahydrofuran and N,N-Dimethylformamide.
Sign Up to like & getrecommendations! Published in 2022 at "Analytica chimica acta"
DOI: 10.1016/j.aca.2022.339531
Abstract: Anthraquinone functional zinc phthalocyanine sensor platform was utilized for ultra-trace amount of water determination in THF and DMF. Using the fluorometric method, the water content in THF was determined with a LOD of 2.27 × 10-4 M and… read more here.
Keywords: phthalocyanine; functional zinc; anthraquinone functional; water ... See more keywords
Immunomodulatory activities of zinc(II)phthalocyanine on the mammalian macrophages through p38 pathway: Potential ex vivo immunomodulatory PDT reagents.
Sign Up to like & getrecommendations! Published in 2019 at "Bioorganic chemistry"
DOI: 10.1016/j.bioorg.2019.103249
Abstract: A series of zinc phthalocyanine having imidazolyl moieties was synthesized. These compounds' immunostimulatory and immunomodulatory activities were tested on the mammalian macrophages in vitro. In the absence of photo induction neither dmso soluble nor the… read more here.
Keywords: immunomodulatory activities; activities zinc; immunomodulatory; mammalian macrophages ... See more keywords
Carboxymethyl chitosan-zinc(II) phthalocyanine conjugates: Synthesis, characterization and photodynamic antifungal therapy.
Sign Up to like & getrecommendations! Published in 2020 at "Carbohydrate polymers"
DOI: 10.1016/j.carbpol.2020.115949
Abstract: Photodynamic antifungal therapy is a promising treatment for increasing drug-resistant fungi. However, low physiological solubility and low fungi-affinity of most potential photosensitizers limits their therapeutic efficacy. To improve the water-solubility and photodynamic antifungal activity of… read more here.
Keywords: antifungal therapy; zinc phthalocyanine; photodynamic antifungal;
Unsymmetrical zinc (II) phthalocyanine and zinc (II) naphthalocyanine with 2,3-Dicyano-1,4-diphenylnaphthalene precursor
Sign Up to like & getrecommendations! Published in 2020 at "Dyes and Pigments"
DOI: 10.1016/j.dyepig.2019.107824
Abstract: Abstract The synthesis, photophysical and photochemical properties of an unsymmetrical zinc (II) phthalocyanine and zinc (II) naphthalocyanine derivative are described. The precursor 2,3-Dicyano-1,4-diphenylnaphthalene was synthetized by Diels-Alder reaction with 1,3-diphenylisobenzofuran and fumaronitrile. The macrocycles were… read more here.
Keywords: zinc naphthalocyanine; dicyano diphenylnaphthalene; zinc; phthalocyanine zinc ... See more keywords
Menthol modified zinc(II) phthalocyanine regioisomers and their photoinduced antimicrobial activity against Staphylococcus aureus
Sign Up to like & getrecommendations! Published in 2021 at "Dyes and Pigments"
DOI: 10.1016/j.dyepig.2021.109410
Abstract: Abstract Our study is the first to investigate the antimicrobial activity of the single regioisomers rather than the mixture of isomeric phthalocyanines - regioisomers with symmetry C4, C1 and C2, functionalized with L-menthol in the… read more here.
Keywords: phthalocyanine regioisomers; activity staphylococcus; antimicrobial activity; phthalocyanine ... See more keywords
An integrin-targeting glutathione-activated zinc(II) phthalocyanine for dual targeted photodynamic therapy.
Sign Up to like & getrecommendations! Published in 2019 at "European journal of medicinal chemistry"
DOI: 10.1016/j.ejmech.2019.04.049
Abstract: A zinc(II) phthalocyanine substituted with three 2,4-dinitrobenzenesulfonate (DNBS) groups and a cyclic arginine-glycine-aspartic acid (cRGDfK) moiety was prepared and characterized. With three strongly electron-withdrawing DNBS groups, this compound was fully quenched in terms of fluorescence… read more here.
Keywords: integrin targeting; photodynamic therapy; targeted photodynamic; zinc phthalocyanine ... See more keywords
Preparation of Zinc (II) phthalocyanine-based LB thin film: Experimental characterization, the determination of some optical properties and the investigation of the optical sensing ability
Sign Up to like & getrecommendations! Published in 2021 at "Optik"
DOI: 10.1016/j.ijleo.2021.167661
Abstract: Abstract Zinc(II) phthalocyanine (Zn(II)Pc) molecule was the first time prepared onto three different substrates utilizing Langmuir-Blodgett (LB) deposition technique to investigate its vapor sensing abilities and some optical properties. We utilized five different and well-known… read more here.
Keywords: film; optical properties; preparation zinc; zinc phthalocyanine ... See more keywords
Zinc phthalocyanine‐soybean phospholipid complex based drug carrier for switchable photoacoustic/fluorescence image, multiphase photothermal/photodynamic treatment and synergetic therapy
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Controlled Release"
DOI: 10.1016/j.jconrel.2018.06.005
Abstract: ABSTRACT For the purpose of precision theranostic of tumor, multifunctional drug delivery systems are always receiving great attentions. Here, we developed a zinc phthalocyanine‐soybean phospholipid (ZnPc‐SPC) complex based drug delivery system with doxorubicin (Dox) as… read more here.
Keywords: image; drug; complex; therapy ... See more keywords
Synthesis, structural characterization, and investigation on photophysical and photochemical features of new metallophthalocyanines
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Luminescence"
DOI: 10.1016/j.jlumin.2018.08.043
Abstract: Abstract In this report, the 3,7,11-trimethyl-2,6,10-dodecatrien-1-ol group was substituted to the peripheral positions of the phthalocyanine macrocycle for obtaining copper (II) 4, cobalt (II) 5 and zinc (II) 6 phthalocyanine derivatives starting from the phthalonitrile… read more here.
Keywords: silicon phthalocyanine; synthesis structural; photophysical photochemical; phthalocyanine ... See more keywords