The Zinc Transporter SLC39A10 Plays an Essential Role in Embryonic Hematopoiesis.
Sign Up to like & getrecommendations! Published in 2023 at "Advanced science"
DOI: 10.1002/advs.202205345
Abstract: The role of zinc in hematopoiesis is currently unclear. Here, SLC39A10 (ZIP10) is identified as a key zinc transporter in hematopoiesis. The results show that in zebrafish, Slc39a10 is a key regulator of the response… read more here.
Keywords: zinc deficiency; zinc transporter; zinc; role ... See more keywords
Pancreatic imaging using an antibody fragment targeting the zinc transporter type 8: a direct comparison with radio-iodinated Exendin-4
Sign Up to like & getrecommendations! Published in 2017 at "Acta Diabetologica"
DOI: 10.1007/s00592-017-1059-x
Abstract: AbstractAim The zinc transporter 8 (ZnT8) has been suggested as a suitable target for non-invasive visualization of the functional pancreatic beta cell mass, due to both its pancreatic beta cell restricted expression and tight involvement… read more here.
Keywords: comparison radio; direct comparison; ab31; znt8 ... See more keywords
Importance of Zinc Transporter 8 Autoantibody in the Diagnosis of Type 1 Diabetes in Latin Americans
Sign Up to like & getrecommendations! Published in 2017 at "Scientific Reports"
DOI: 10.1038/s41598-017-00307-4
Abstract: There is a scarcity of data of zinc transporter-8 autoantibody (ZnT8A) on mixed populations such as Brazilian. Therefore, we evaluated the relevance of ZnT8A for type 1 diabetes (T1D) diagnosis and the role of ZnT8… read more here.
Keywords: znt8a; diagnosis; type diabetes; transporter autoantibody ... See more keywords
Zinc and the Zinc Transporter SLC39A10/ZIP10 Are Required for Heme Synthesis in Developing Erythroid Progenitors
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DOI: 10.1093/cdn/nzab059_021
Abstract: Zinc is an essential nutrient for diverse biological processes in the body. Cellular zinc homeostasis is established through differential expressions of the transmembrane zinc transporter proteins, ZnTs and ZIPs. The aims of the current studies… read more here.
Keywords: zip10; g1e er4; zinc transporter; heme synthesis ... See more keywords
Zinc transporter ZIP13 suppresses beige adipocyte biogenesis and energy expenditure by regulating C/EBP-β expression
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DOI: 10.1371/journal.pgen.1006950
Abstract: Given the relevance of beige adipocytes in adult humans, a better understanding of the molecular circuits involved in beige adipocyte biogenesis has provided new insight into human brown adipocyte biology. Genetic mutations in SLC39A13/ZIP13, a… read more here.
Keywords: zinc transporter; beige adipocyte; adipocyte biogenesis; zip13 ... See more keywords
Zinc Transporter 8 Autoantibodies (ZnT8A) and a Type 1 Diabetes Genetic Risk Score Can Exclude Individuals With Type 1 Diabetes From Inappropriate Genetic Testing for Monogenic Diabetes
Sign Up to like & getrecommendations! Published in 2018 at "Diabetes Care"
DOI: 10.2337/dc18-0373
Abstract: We have recently shown that the detection of monogenic diabetes in a population can be improved by excluding individuals with type 1 diabetes (T1D) identified by having low C-peptide levels and/or the presence of GAD… read more here.
Keywords: individuals type; transporter autoantibodies; autoantibodies znt8a; type diabetes ... See more keywords
Variants in the zinc transporter-3 encoding gene (SLC30A3) in schizophrenia and bipolar disorder: Effects on brain glutamate–A pilot study
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Psychiatry"
DOI: 10.3389/fpsyt.2022.929306
Abstract: Zinc transporter 3 (ZnT3) has been implicated in the aetiopathology of schizophrenia. In this pilot study, we tested the hypothesis that the presence of a minor allele of two variants in the gene encoding ZnT3… read more here.
Keywords: zinc transporter; glutamate; brain; study ... See more keywords