A15063 Increased expression of zinc transporter ZIP12 in pulmonary arterial hypertension induced by monocrotaline
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Hypertension"
DOI: 10.1097/01.hjh.0000548046.87897.b6
Abstract: Objectives: Previous study identified ZIP12 as a major regulator of hypoxia-induced pulmonary arterial hypertension (PAH), however, it remains to determine the role of ZIP12 in monocrotaline (MCT)-induced PAH. Methods: PAH was induced by intraperitoneal injection… read more here.
Keywords: zinc; arterial hypertension; pulmonary arterial; zip12 ... See more keywords
ZIP12 Contributes to Hypoxic Pulmonary Hypertension by Driving Phenotypic Switching of Pulmonary Artery Smooth Muscle Cells.
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DOI: 10.1097/fjc.0000000000001156
Abstract: ABSTRACT ZIP12, a plasmalemmal zinc transporter, reportedly promotes pulmonary vascular remodeling (PVR) by enhancing proliferation of pulmonary artery smooth muscle cells (PASMCs). However, the mechanisms of ZIP12 facilitating PASMCs proliferation remain incompletely appreciated. It has… read more here.
Keywords: zip12; phenotypic switching; proliferation; switching pasmcs ... See more keywords