Ziprasidone Induces Rabbit Atrium Arrhythmogenesis via Modification of Oxidative Stress and Sodium/Calcium Homeostasis
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DOI: 10.3390/biomedicines10050976
Abstract: Background: Atypical antipsychotics increase the risk of atrial arrhythmias and sudden cardiac death. This study investigated whether ziprasidone, a second-generation antipsychotic, affected intracellular Ca2+ and Na+ regulation and oxidative stress, providing proarrhythmogenic substrates in atriums.… read more here.
Keywords: ziprasidone; oxidative stress; ziprasidone treated; atrial myocytes ... See more keywords