Sodium zirconium cyclosilicate for the management of chronic hyperkalemia in kidney disease, a novel agent
Sign Up to like & getrecommendations! Published in 2021 at "Expert Review of Clinical Pharmacology"
DOI: 10.1080/17512433.2021.1932460
Abstract: ABSTRACT Introduction Hyperkalemia is a common finding in patients with advanced kidney disease for multiple reasons. Renin-Angiotensin-Aldosterone-System Inhibitors (RAASi) that are indicated for slowing down progression of kidney disease are often associated with hyperkalemia which… read more here.
Keywords: sodium zirconium; hyperkalemia; zirconium cyclosilicate; kidney disease ... See more keywords
Zirconium cyclosilicate: An oral sorbent for potassium, four decades in the making.
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DOI: 10.1111/aor.14248
Abstract: HemoCleanse collaborated with Dr. John Sherman and Union Carbide in the 1980s to develop a cation exchanger with high selectivity for potassium and ammonium, for use in a wearable artificial kidney. Synthetic zeolites had unexpected… read more here.
Keywords: cyclosilicate oral; sorbent potassium; zirconium cyclosilicate; oral sorbent ... See more keywords
Hyperkalaemia and potassium binders: Retrospective observational analysis looking at the efficacy and cost effectiveness of calcium polystyrene sulfonate and sodium zirconium cyclosilicate
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Clinical Pharmacy and Therapeutics"
DOI: 10.1111/jcpt.13766
Abstract: Hyperkalaemia is a common medical emergency in patients admitted to hospital. There is a limited evidence base supporting some of the commonly applied treatment strategies. Although, NICE has recommended the use of sodium zirconium cyclosilicate… read more here.
Keywords: calcium polystyrene; hyperkalaemia; zirconium cyclosilicate; sodium zirconium ... See more keywords
Comparison of Sodium Zirconium Cyclosilicate to Sodium Polystyrene Sulfonate in the Inpatient Management of Acute Hyperkalemia.
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DOI: 10.1177/08971900231176462
Abstract: BACKGROUND Oral potassium binders have a role in the management of acute hyperkalemia among hospitalized patients. However, with therapeutic additions to this class, there is insufficient evidence between potassium binders to support a standard of… read more here.
Keywords: potassium; zirconium cyclosilicate; sodium; sodium zirconium ... See more keywords