NCI 8628: A randomized phase 2 study of ziv‐aflibercept and high‐dose interleukin 2 or high‐dose interleukin 2 alone for inoperable stage III or IV melanoma
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DOI: 10.1002/cncr.31734
Abstract: Interleukin 2 (IL‐2) is a growth factor for T and natural killer cells, promotes proinflammatory cytokines, and can lead to durable responses in patients with melanoma. Vascular endothelial growth factor (VEGF) promotes angiogenesis and modulates… read more here.
Keywords: ziv aflibercept; high dose; dose interleukin; nci 8628 ... See more keywords
The sterility, stability and efficacy of repackaged ziv-aflibercept for intravitreal administration
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DOI: 10.1038/s41598-022-06831-2
Abstract: To evaluate the sterility, stability, and efficacy of repackaged ziv-aflibercept in 1-mL plastic tuberculin syringes for intravitreal injection after storage for up to 90 days at controlled (4 °C) and ambient (25.8 °C) temperature. A… read more here.
Keywords: stability efficacy; repackaged ziv; ziv; ziv aflibercept ... See more keywords
Virtual reality‐based proficiency test in direct ophthalmoscopy
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DOI: 10.1111/aos.13546
Abstract: Ophthalmol 94: e669. Chan EW, Eldeeb M, Dedhia CJ, Mansour A & Chhablani J (2017): One-year treatment outcomes of ziv-aflibercept for treatmentna€ıve macular oedema in branch retinal vein occlusion. Acta Ophthalmol [Epub ahead of print].… read more here.
Keywords: ziv aflibercept; reality based; ophthalmology; ahead print ... See more keywords
Phase IB study of ziv-aflibercept plus pembrolizumab in patients with advanced solid tumors
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DOI: 10.1136/jitc-2021-003569
Abstract: Background The combination of antiangiogenic agents with immune checkpoint inhibitors could potentially overcome immune suppression driven by tumor angiogenesis. We report results from a phase IB study of ziv-aflibercept plus pembrolizumab in patients with advanced… read more here.
Keywords: aflibercept plus; ziv; ziv aflibercept; plus pembrolizumab ... See more keywords
Safety of intravitreal ziv-aflibercept in choroido-retinal vascular diseases: A randomised double-blind intervention study
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DOI: 10.1371/journal.pone.0223944
Abstract: Aim To evaluate the safety of 1.25mg and 2mg intravitreal ziv-aflibercept (IVZ) in Ghanaian eyes with choroido-retinal vascular diseases. Design Prospective, randomised, double blind, interventional study. Methods Twenty patients with centre involving macular oedema in… read more here.
Keywords: retinal vascular; intravitreal ziv; ziv aflibercept; safety ... See more keywords
Effectiveness of the Use of Three-Dose Intravitreal Ziv-Aflibercept in the Management of Diabetic Macular Edema in a Real-Life Setting.
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DOI: 10.2147/opth.s398359
Abstract: Purpose It has been reported that intravitreal Ziv-aflibercept is a safe and effective drug for the treatment of diabetes macular edema (DME). The objective of this study was to evaluate in a real-life setting, the… read more here.
Keywords: intravitreal ziv; real life; ziv aflibercept; macular edema ... See more keywords
Intravitreal Ziv‐Aflibercept: Clinical Effects and Economic Impact
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DOI: 10.22608/apo.2017263
Abstract: Abstract: During the past decade, drugs that inhibit the actions of vascular endothelial growth factor (VEGF) have become standard‐of‐care treatment for a variety of chorioretinal vascular conditions. The off‐label, intravitreal use of ziv‐aflibercept (Zaltrap) has… read more here.
Keywords: intravitreal ziv; ziv aflibercept; clinical effects; ziv ... See more keywords