Zn2+-induced disruption of neuronal mitochondrial function: Synergism with Ca2+, critical dependence upon cytosolic Zn2+ buffering, and contributions to neuronal injury
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DOI: 10.1016/j.expneurol.2018.01.012
Abstract: ABSTRACT Excitotoxic Zn2+ and Ca2+ accumulation contributes to neuronal injury after ischemia or prolonged seizures. Synaptically released Zn2+ can enter postsynaptic neurons via routes including voltage sensitive Ca2+ channels (VSCC), and, more rapidly, through Ca2+… read more here.
Keywords: zn2 buffering; disruption; neuronal injury; ca2 ... See more keywords