Deciphering the functional mechanism of zinc ions of PARP1 binding with single strand breaks and double strand breaks
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DOI: 10.1039/d2ra02683j
Abstract: Poly(ADP-ribose)polymerase 1 (PARP1) is a key target for the treatment of cancer-related diseases, and plays an important role in biological processes such as DNA repair, regulating a variety of metabolic and signal transduction processes. Understanding… read more here.
Keywords: znf1 znf2; strand breaks; dna; zinc ions ... See more keywords