Zinc Finger Protein 263 Augments Autophagy and Promotes Intrahepatic Cholangiocarcinoma Proliferation
Sign Up to like & getrecommendations! Published in 2024 at "Molecular Carcinogenesis"
DOI: 10.1002/mc.23847
Abstract: Intrahepatic cholangiocarcinoma (ICC) is an aggressive cancer characterized by a poor prognosis. Despite Zinc finger proteins (ZNFs) importance in tumor development and progression, it is unknown how dysregulated ZNF263 contributes to intrahepatic cholangiocarcinoma. This study… read more here.
Keywords: zinc finger; znf263; intrahepatic cholangiocarcinoma; cholangiocarcinoma ... See more keywords
Transcription factor ZNF263 primes human embryonic stem cells for pluripotency dissolution and lineage commitment
Sign Up to like & getrecommendations! Published in 2025 at "Nature Communications"
DOI: 10.1038/s41467-025-64290-5
Abstract: Conventional human embryonic stem cells (hESCs) are capable of self-renewal and simultaneously poised for differentiation. But the mechanisms underlying this primed pluripotent state, which endows them with elevated responsiveness to differentiation cues, remain largely underexplored.… read more here.
Keywords: differentiation; znf263; pluripotency; stem cells ... See more keywords