GLTSCR1 coordinates alternative splicing and transcription elongation of ZO1 to regulate colorectal cancer progression.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of molecular cell biology"
DOI: 10.1093/jmcb/mjac009
Abstract: Alternative splicing (AS) and transcription elongation are vital biological processes, and their dysregulation causes multiple diseases, including tumors. However, the co-regulatory mechanism of AS and transcription elongation in tumors remains unclear. This study demonstrates a… read more here.
Keywords: elongation; transcription elongation; zo1; alternative splicing ... See more keywords
The Cx43 Carboxyl-Terminal Mimetic Peptide αCT1 Protects Endothelial Barrier Function in a ZO1 Binding-Competent Manner
Sign Up to like & getrecommendations! Published in 2021 at "Biomolecules"
DOI: 10.3390/biom11081192
Abstract: The Cx43 carboxyl-terminus (CT) mimetic peptide, αCT1, originally designed to bind to Zonula Occludens 1 (ZO1) and thereby inhibit Cx43/ZO1 interaction, was used as a tool to probe the role of Cx43/ZO1 association in regulation… read more here.
Keywords: cx43; ct1; barrier function; zo1 ... See more keywords