β-Catenin and FGFR2 regulate postnatal rosette-based adrenocortical morphogenesis
Sign Up to like & getrecommendations! Published in 2020 at "Nature Communications"
DOI: 10.1038/s41467-020-15332-7
Abstract: Rosettes are widely used in epithelial morphogenesis during embryonic development and organogenesis. However, their role in postnatal development and adult tissue maintenance remains largely unknown. Here, we show zona glomerulosa cells in the adult adrenal… read more here.
Keywords: rosette; zona glomerulosa; morphogenesis; catenin fgfr2 ... See more keywords
Mechanisms of β-catenin-induced adrenal hyperplasia
Sign Up to like & getrecommendations! Published in 2020 at "Nature Reviews Endocrinology"
DOI: 10.1038/s41574-020-0369-1
Abstract: Nature reviews | Endocrinology Original article Pignatti, E. et al. Beta-catenin causes adrenal hyperplasia by blocking zonal trans differentiation. Cell Reports. 31, 107524 (2020) somatic β-catenin gain-of-function (βcat-GOF) mutations are known to drive adrenal hyperplasia… read more here.
Keywords: catenin; zona glomerulosa; cat gof; zona ... See more keywords
Changes of the CYP11B2 Expressing Zona Glomerulosa in Human Adrenals From Birth to 40 Years of Age
Sign Up to like & getrecommendations! Published in 2022 at "Hypertension"
DOI: 10.1161/hypertensionaha.122.19052
Abstract: Background: Aldosterone synthase (CYP11B2) antibodies for immunohistochemistry, enables to visualize aldosterone-producing zona glomerulosa (ZG), aldosterone-producing micronodules, and aldosterone-producing adenomas. The architecture of the ZG differs in old versus young age but the evolution of the… read more here.
Keywords: aldosterone producing; area; zona glomerulosa; age ... See more keywords