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   Articles with "zona pellucida" as a keyword



Obesity results with smaller oocyte in in vitro fertilization/intracytoplasmic sperm injection cycles—a prospective study

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recommendations! Published in 2017 at "Journal of Assisted Reproduction and Genetics"

DOI: 10.1007/s10815-017-0975-6

Abstract: BackgroundObesity is associated with several fertility disorders. This prospective cohort study was designed to evaluate the effect of body mass index (BMI) (kg/m2) on oocyte diameter and treatment.MethodsWomen undergoing in vitro fertilization (IVF) with intracytoplasmic… read more here.

Keywords: intracytoplasmic sperm; sperm injection; vitro fertilization; study ... See more keywords

A novel homozygous nonsense mutation in zona pellucida 1 (ZP1) causes human female empty follicle syndrome

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recommendations! Published in 2021 at "Journal of Assisted Reproduction and Genetics"

DOI: 10.1007/s10815-021-02136-x

Abstract: To identify a pathogenic gene mutation in a female infertility proband characterized by empty follicle syndrome (EFS) and explore the genetic cause of EFS. Whole exome sequencing (WES) was performed to identify the candidate pathogenic… read more here.

Keywords: zp1; empty follicle; mutation; zona pellucida ... See more keywords

Efficient production of human zona pellucida-3 in a prokaryotic expression system

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recommendations! Published in 2018 at "World Journal of Microbiology and Biotechnology"

DOI: 10.1007/s11274-018-2521-9

Abstract: The zona pellucida-3 (ZP3) protein plays a pivotal role in oocyte and gamete development. We aimed to produce a recombinant ZP3 peptide using the Escherichia coli secretory system and apply it to a protein chip… read more here.

Keywords: protein chip; zp3; system; zona pellucida ... See more keywords

Characterization of a mutation in the zona pellucida module of Endoglin that causes Hereditary Hemorrhagic Telangiectasia.

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recommendations! Published in 2019 at "Gene"

DOI: 10.1016/j.gene.2019.02.016

Abstract: Hereditary hemorrhagic telangiectasia (HHT) is a vascular rare disease characterized by nose and gastrointestinal bleeding, skin and mucosa telangiectasias, and arteriovenous malformations in internal organs. HHT shows an autosomal dominant inheritance and a worldwide prevalence… read more here.

Keywords: mutation; hereditary hemorrhagic; pellucida module; hemorrhagic telangiectasia ... See more keywords

Type 1 diabetes affects zona pellucida and genome methylation in oocytes and granulosa cells

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recommendations! Published in 2020 at "Molecular and Cellular Endocrinology"

DOI: 10.1016/j.mce.2019.110627

Abstract: Diabetes affects oocyte nuclear and cytoplasmic quality. In this study, we generated a type 1 diabetes (T1D) mouse model by STZ injection to study the effects of T1D on zona pellucida and genomic DNA methylation… read more here.

Keywords: granulosa cells; methylation; oocytes granulosa; type diabetes ... See more keywords

Zona pellucida blocks adenovirus from entering porcine oocytes.

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recommendations! Published in 2019 at "Theriogenology"

DOI: 10.1016/j.theriogenology.2019.03.008

Abstract: Adenovirus is a kind of non-enveloped,double-stranded DNA virus. As a member of the mammalian adenoviruses of the Adenoviridae family, porcine adenovirus causes gastrointestinal disease in piglets. In this study, the modified adenovirus was manipulated to… read more here.

Keywords: porcine oocytes; modified adenovirus; zona pellucida; porcine ... See more keywords

Hyperelastic models for the human zona pellucida and their implications on shear modulus estimation in the clinical practice

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recommendations! Published in 2024 at "Scientific Reports"

DOI: 10.1038/s41598-024-83042-x

Abstract: It has long been speculated that the mechanical properties of the human oocyte can be an indicator for oocyte viability. Recent studies have demonstrated that embryo implantation rates, following Intra-Cytoplasmic Sperm Injection (ICSI) procedures, may… read more here.

Keywords: zona pellucida; oocyte; hyperelastic models; shear modulus ... See more keywords

An Alternative Way to Improve Mammalian Embryo Development In Vitro: Culture of Zona Pellucida-Free Embryos.

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recommendations! Published in 2022 at "Cellular reprogramming"

DOI: 10.1089/cell.2022.0012

Abstract: An increasing number of data proves that the presence of the zona pellucida is not essential to mammalian embryo production, including maturation, fertilization, and embryo culture. In fact, the structure of the zona pellucida of… read more here.

Keywords: culture; zona pellucida; zona; free embryos ... See more keywords

Mutant Zp1 impedes incorporation of ZP3 and ZP4 in the zona pellucida, resulting in zona absence and female infertility in rats†

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recommendations! Published in 2021 at "Biology of Reproduction"

DOI: 10.1093/biolre/ioab025

Abstract: Abstract The zona pellucida (ZP) plays vital roles in reproductive processes including oogenesis, fertilization, and preimplantation development. Both human and rat ZP consist of four glycoproteins, called ZP1, ZP2, ZP3, and ZP4. Our previous research… read more here.

Keywords: infertility; zp1; zp3 zp4; zona pellucida ... See more keywords

Zona pellucida removal by acid Tyrode's solution affects pre- and post-implantation development and gene expression in mouse embryos

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recommendations! Published in 2022 at "Biology of Reproduction"

DOI: 10.1093/biolre/ioac155

Abstract: Abstract The zona pellucida plays a crucial role in the process of fertilization to early embryonic development, including cellular arrangement and communication between blastomeres. However, little is known regarding the role of the zona pellucida… read more here.

Keywords: post implantation; development; zona; zona pellucida ... See more keywords

Initial detachment of the mouse oocyte from the zona pellucida is mediated by metallopeptidase activity

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recommendations! Published in 2022 at "Biology of Reproduction"

DOI: 10.1093/biolre/ioac185

Abstract: Abstract The fully grown mammalian oocyte is tightly attached to its extracellular matrix shell, the zona pellucida (ZP), but the oocyte detaches from the ZP shortly after ovulation is signaled. The mechanism by which the… read more here.

Keywords: metallopeptidase activity; zona pellucida; oocyte; mouse oocyte ... See more keywords