Active Role of the Necrotic Zone in Desensitization of Hypoxic Macrophages and Regulation of CSC-Fate: A hypothesis
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DOI: 10.3389/fonc.2018.00235
Abstract: Fast-proliferating cancer cells in the hypoxic region face a shortage of oxygen and nutrients, undergo necrotic cell death, and release numerous signaling components. Hypoxia-induced chemo-attractants signal for macrophages/monocytes to clear debris and return the system… read more here.
Keywords: necrotic zone; role necrotic; desensitization hypoxic; zone desensitization ... See more keywords