Articles with "zone designs" as a keyword



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Optimal adaptive promising zone designs

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Published in 2022 at "Statistics in Medicine"

DOI: 10.1002/sim.9339

Abstract: We develop optimal decision rules for sample size re‐estimation in two‐stage adaptive group sequential clinical trials. It is usual for the initial sample size specification of such trials to be adequate to detect a realistic… read more here.

Keywords: sample size; power; zone designs; zone ... See more keywords