Articles with "zonulin" as a keyword



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Serum zonulin level is not elevated in patients with polycystic ovary syndrome without metabolic syndrome

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Published in 2019 at "Archives of Gynecology and Obstetrics"

DOI: 10.1007/s00404-019-05345-z

Abstract: Polycystic ovary syndrome (PCOS) is a complex disorder with gynecological, metabolic and carcinogenic effects. Increased intestinal permeability is related with obesity, insulin resistance, type 1 and 2 diabetes mellitus. The existence of such a relationship… read more here.

Keywords: polycystic ovary; pcos; cholesterol; metabolic syndrome ... See more keywords
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Zonulin, inflammation and iron status in patients with early stages of chronic kidney disease

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Published in 2017 at "International Urology and Nephrology"

DOI: 10.1007/s11255-017-1741-5

Abstract: Background/aimsZonulin is the only known regulator of intestinal permeability. It is also considered as a potential inflammatory marker in several conditions such as diabetes and inflammatory bowel syndrome. The aim of the study was to… read more here.

Keywords: patients early; iron status; inflammation; zonulin ... See more keywords
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A polyphenol-rich dietary pattern improves intestinal permeability, evaluated as serum zonulin levels, in older subjects: The MaPLE randomised controlled trial.

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Published in 2020 at "Clinical nutrition"

DOI: 10.1016/j.clnu.2020.12.014

Abstract: BACKGROUND & AIM Increased intestinal permeability (IP) can occur in older people and contribute to the activation of the immune system and inflammation. Dietary interventions may represent a potential strategy to reduce IP. In this… read more here.

Keywords: intervention; serum zonulin; trial; zonulin levels ... See more keywords
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Fecal zonulin is elevated in Crohn’s disease and in cigarette smokers

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Published in 2017 at "Practical Laboratory Medicine"

DOI: 10.1016/j.plabm.2017.09.001

Abstract: Objectives Human zonulin is a protein that increases permeability in the epithelial layer of the small intestine by reversibly modulating the intercellular tight junctions. There is not sufficient information available about zonulin's participation in inflammatory… read more here.

Keywords: serum zonulin; fecal zonulin; cigarette smokers; zonulin ... See more keywords
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Zonulin levels in complicated pregnancy: a systematic review and meta-analysis

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Published in 2022 at "Journal of Obstetrics and Gynaecology"

DOI: 10.1080/01443615.2022.2114822

Abstract: Abstract Zonulin is a novel biomarker of intestinal permeability. The existing data suggest that upregulation of zonulin might be linked to systemic inflammation and pregnancy complications. A systematic search was performed in medical electronic databases… read more here.

Keywords: zonulin levels; meta analysis; levels complicated; pregnancy ... See more keywords
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Weight loss via a low-carbohydrate diet improved the intestinal permeability marker, zonulin, in prostate cancer patients

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Published in 2022 at "Annals of Medicine"

DOI: 10.1080/07853890.2022.2069853

Abstract: Abstract Background Accumulating evidence suggest that gut microbiota may impact urologic health including prostate cancer (PC), potentially via affecting intestinal permeability (IP). Studies have indicated that disrupted IP may be improved by healthy diets and… read more here.

Keywords: prostate; prostate cancer; intestinal permeability; zonulin ... See more keywords
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The Zonulin-transgenic mouse displays behavioral alterations ameliorated via depletion of the gut microbiota.

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Published in 2021 at "Tissue barriers"

DOI: 10.1080/21688370.2021.2000299

Abstract: The gut-brain axis hypothesis suggests that interactions in the intestinal milieu are critically involved in regulating brain function. Several studies point to a gut-microbiota-brain connection linking an impaired intestinal barrier and altered gut microbiota composition… read more here.

Keywords: depletion; brain; gut microbiota; zonulin ... See more keywords
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P0868ZONULIN AS A THERAPEUTIC POTENTIAL BIOMARKER OF ANEMIA IN PATIENTS WITH MULTIPLE MYELOMA AND CHRONIC KIDNEY DISEASE

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Published in 2020 at "Nephrology Dialysis Transplantation"

DOI: 10.1093/ndt/gfaa142.p0868

Abstract: Zonulin is a haptoglobin 2 precursor, that regulates the intestinal permeability. As a double-chain form it takes part in scavenging haemoglobin. Chronic inflammation is common complication of chronic kidney disease which affects iron metabolism. The… read more here.

Keywords: chronic kidney; biomarker; kidney disease; zonulin ... See more keywords
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Evaluation of plasma zonulin level and its relationship with inflammatory cytokines in patients with vitiligo

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Published in 2022 at "Journal of Cosmetic Dermatology"

DOI: 10.1111/jocd.15493

Abstract: It has been proven that there is an increase in intestinal permeability in some autoimmune diseases. In our study, we purposed to assess intestinal permeability in vitiligo disease by looking at zonulin levels. At the… read more here.

Keywords: zonulin level; evaluation plasma; inflammatory cytokines; level relationship ... See more keywords
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The acute effects of nonstructural-1 protein dengue virus type 2 on wet liver weight, zonulin expression and serum zonulin

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Published in 2023 at "Iranian Journal of Microbiology"

DOI: 10.18502/ijm.v15i2.12483

Abstract: Background and Objectives: Intestinal leakage commonly occurs in severe dengue infection with zonulin as a biomarker. The aim of this study was to determine the effects of NS1 on liver weight, zonulin expression and serum… read more here.

Keywords: weight zonulin; serum zonulin; expression; liver weight ... See more keywords
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The therapeutic use of the zonulin inhibitor AT-1001 (Larazotide) for a variety of acute and chronic inflammatory diseases.

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Published in 2021 at "Current medicinal chemistry"

DOI: 10.2174/0929867328666210104110053

Abstract: BACKGROUND The involvement of intercellular tight junctions and, in particular, the modulation of their competency by the zonulin pathway with a subsequent increase in epithelial and endothelial permeability, has been described in several chronic and… read more here.

Keywords: acute; therapeutic use; inflammatory diseases; zonulin ... See more keywords