Articles with "zorifertinib" as a keyword



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Profiling of in vivo, in vitro and reactive zorifertinib metabolites using liquid chromatography ion trap mass spectrometry

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Published in 2022 at "RSC Advances"

DOI: 10.1039/d2ra02848d

Abstract: Zorifertinib (AZD-3759; ZFB) is a potent, novel, oral, small molecule used for the treatment of non-small cell lung cancer (NSCLC). ZFB is Epidermal Growth Factor Receptor (EGFR) inhibitor that is characterized by good permeability of… read more here.

Keywords: phase; phase metabolites; vivo phase; zorifertinib ... See more keywords