Structural basis of ZP2-targeted female nonhormonal contraception
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DOI: 10.1073/pnas.2426057122
Abstract: Monoclonal antibody IE-3 prevents mouse fertilization by binding ZP2, a major component of the oocyte-specific zona pellucida (ZP). We show that an IE-3-derived single-chain variable fragment (scFV) is sufficient for blocking fertilization in vitro and… read more here.
Keywords: zp2; structural basis; zp2 targeted; targeted female ... See more keywords