A novel mutation in ZP3 causes empty follicle syndrome and abnormal zona pellucida formation
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Assisted Reproduction and Genetics"
DOI: 10.1007/s10815-020-01995-0
Abstract: Purpose To identify disease-causing genes involved in female infertility. Methods Whole-exome sequencing and Sanger DNA sequencing were used to identify the mutations in disease-causing genes. We performed subcellular protein localization, western immunoblotting analysis, and co-immunoprecipitation… read more here.
Keywords: follicle syndrome; novel mutation; zp3; female infertility ... See more keywords
Novel mutations in ZP2 and ZP3 cause female infertility in three patients
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DOI: 10.1007/s10815-022-02466-4
Abstract: The aim of this study was to identify the disease-causing mutations found in three infertile female patients who were diagnosed with abnormal zona pellucida (ZP) and empty follicle syndrome (EFS). We performed whole-exome sequencing and… read more here.
Keywords: zp3; infertility; gene; mutations zp2 ... See more keywords
Efficient production of human zona pellucida-3 in a prokaryotic expression system
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DOI: 10.1007/s11274-018-2521-9
Abstract: The zona pellucida-3 (ZP3) protein plays a pivotal role in oocyte and gamete development. We aimed to produce a recombinant ZP3 peptide using the Escherichia coli secretory system and apply it to a protein chip… read more here.
Keywords: protein chip; zp3; system; zona pellucida ... See more keywords
Abstract 3937: An intracellular variant of zona pellucida glycoprotein 3 is expressed in cancer
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DOI: 10.1158/1538-7445.am2023-3937
Abstract: This study describes the expression of an intracellular variant of the Zona Pellucida glycoprotein 3 (ZP3) that is predominantly expressed in cancer. ZP3 is an important constituent of the Zona Pellucida (ZP), the extracellular layer… read more here.
Keywords: zp3; zp3 cancer; zona pellucida; expression ... See more keywords