Identification of a novel hypermethylation marker, ZSCAN18, and construction of a diagnostic model in cervical cancer
Sign Up to like & getrecommendations! Published in 2025 at "Clinical and Translational Oncology"
DOI: 10.1007/s12094-025-03864-7
Abstract: Cervical cancer (CC), a common female malignancy, has been linked to alterations in DNA methylation. This study employed an integrated "dry-wet lab" strategy combining bioinformatics, machine learning, and experimental validation to identify novel methylation biomarkers… read more here.
Keywords: zscan18; methylation; diagnostic model; cervical cancer ... See more keywords
Zinc finger and SCAN domain-containing protein 18 is a potential DNA methylation-modified tumor suppressor and biomarker in breast cancer
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Endocrinology"
DOI: 10.3389/fendo.2023.1095604
Abstract: Introduction Zinc finger and SCAN domain-containing protein 18 (ZSCAN18) has been investigated as a putative biomarker of multiple human cancers. However, the expression profile, epigenetic modification, prognostic value, transcription regulation, and molecular mechanism of ZSCAN18… read more here.
Keywords: tumor; zscan18; dna methylation; expression ... See more keywords