ZSCAN4 facilitates chromatin remodeling and promotes the cancer stem cell phenotype
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DOI: 10.1038/s41388-020-1333-1
Abstract: Cancer stem cells (CSCs) are cells within tumors that maintain the ability to self-renew, drive tumor growth, and contribute to therapeutic resistance and cancer recurrence. In this study, we investigate the role of Zinc finger… read more here.
Keywords: phenotype; csc; cancer stem; zscan4 ... See more keywords
RBIO-10. Targeting telomere maintenance sensitizes group 3 medulloblastomas to ionizing radiation
Sign Up to like & getrecommendations! Published in 2025 at "Neuro-Oncology"
DOI: 10.1093/neuonc/noaf201.1550
Abstract: Ionizing radiation (IR) is part of standard care for group 3 (G3) medulloblastomas (MBs), the most aggressive molecular subtype of the most common malignant pediatric brain cancer. However, IR is often not curative and causes… read more here.
Keywords: zscan4; maintenance; ionizing radiation; telomere maintenance ... See more keywords