The Phosphodiesterase-9A inhibitor PF04447943 improves coronary microvascular rarefaction via Peroxiredoxin-5 in the ZSF1 rat model of HFpEF
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DOI: 10.1152/physiol.2023.38.s1.5733071
Abstract: Coronary microvascular dysfunction contributes to the development of left ventricular (LV) diastolic dysfunction in heart failure with preserved ejection fraction (HFpEF), a prevalent symptom that has limited targeted treatment options. Selective pharmacological inhibitors of phosphodiesterase… read more here.
Keywords: zsf1 rat; physiology; rat model; coronary microvascular ... See more keywords