Behavioural, morphological and electrophysiological assessment of the effects of type 2 diabetes mellitus on large and small nerve fibres in Zucker diabetic fatty, Zucker lean and Wistar rats
Sign Up to like & getrecommendations! Published in 2018 at "European Journal of Pain"
DOI: 10.1002/ejp.1235
Abstract: Peripheral neuropathy is a common complication in type 2 diabetes mellitus (T2DM). The most common presentation is in the form of a distal axonal sensory‐motor polyneuropathy that involves large and small nerve fibres in variable… read more here.
Keywords: small nerve; zucker; large small; type diabetes ... See more keywords
Obese male Zucker rats exhibit dendritic remodeling in neurons of the hippocampal trisynaptic circuit as well as spatial memory deficits
Sign Up to like & getrecommendations! Published in 2022 at "Hippocampus"
DOI: 10.1002/hipo.23473
Abstract: Obesity is characterized by excessive fat accumulation. The Zucker rat displays genetic obesity due to a mutation in the leptin receptor gene; this model is of great interest because of its similarity to human obesity.… read more here.
Keywords: zucker; spatial memory; obese male; zucker rats ... See more keywords
Putting the Hindgut Hypothesis to the Test in a Diabetic Zucker Rat Model
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DOI: 10.1007/s11695-019-04079-w
Abstract: The hindgut theory hypothesizes a key role of differential hindgut stimulation following metabolic procedures in ameliorating diabetes mellitus. We used two strategies to remove the hindgut from intestinal continuity in order to analyze its impact… read more here.
Keywords: zucker; hindgut hypothesis; group; diabetes mellitus ... See more keywords
Lipid Metabolism is Closely Associated with Normal Testicular Growth Based on Global Transcriptome Profiles in Normal and Underdeveloped Testis of Obese Zucker (fa/fa) Rats
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DOI: 10.1007/s11745-017-4298-2
Abstract: Zucker (fa/fa) obese rats often have non-identical and differently sized paired testes, leaving one testis underdeveloped. Our earlier study found that the underdeveloped testes, > 30% smaller than the normal ones, have a selective decrease in docosapentaenoic… read more here.
Keywords: obese zucker; testis; zucker; metabolism ... See more keywords
Sleeve Gastrectomy in Obese Zucker Rats Restores Cardiac Function and Geometry Toward a Lean Phenotype Independent of Weight Loss.
Sign Up to like & getrecommendations! Published in 2019 at "Journal of cardiac failure"
DOI: 10.1016/j.cardfail.2019.04.001
Abstract: OBJECTIVE Bariatric surgery, including sleeve gastrectomy (SG), significantly improves cardiac geometry and function in patients with heart failure. In this study, we used the obese Zucker rat as an animal model of heart failure with… read more here.
Keywords: zucker; weight loss; geometry; function ... See more keywords
Effects of acylated and nonacylated anthocyanins extracts on gut metabolites and microbiota in diabetic Zucker rats: A metabolomic and metagenomic study.
Sign Up to like & getrecommendations! Published in 2022 at "Food research international"
DOI: 10.1016/j.foodres.2022.110978
Abstract: Anthocyanins have been shown to have prebiotic properties. This study investigated the impact of nonacylated anthocyanins and acylated anthocyanins on fecal and cecal metabolites and colonic gut microbiota in diabetic state using 1H nuclear magnetic… read more here.
Keywords: microbiota diabetic; effects acylated; zucker; nonacylated anthocyanins ... See more keywords
Dietary intake of cod protein beneficially affects concentrations of urinary markers of kidney function and results in lower urinary loss of amino acids in obese Zucker fa/fa rats
Sign Up to like & getrecommendations! Published in 2018 at "British Journal of Nutrition"
DOI: 10.1017/s0007114518002076
Abstract: Abstract Obesity increases the risk for developing kidney disease, and protection of kidneys through changes in diet should be investigated. Fish intake has been associated with reduced risk of developing kidney disease; therefore, we wanted… read more here.
Keywords: protein; obese zucker; zucker; zucker rats ... See more keywords
Science standards do address scientific literacy: A reply to Zucker and Noyce
Sign Up to like & getrecommendations! Published in 2020 at "Phi Delta Kappan"
DOI: 10.1177/0031721720963232
Abstract: In their article, “Lessons from the pandemic about science education,” Andrew Zucker and Pendred Noyce stress the importance of students making sense of the world around them and use the COVID-19 pandemic as a call… read more here.
Keywords: zucker; science; address; literacy ... See more keywords
Insulin-Regulated Aminopeptidase Inhibition Ameliorates Metabolism in Obese Zucker Rats
Sign Up to like & getrecommendations! Published in 2020 at "Frontiers in Molecular Biosciences"
DOI: 10.3389/fmolb.2020.586225
Abstract: The aim of our study was to determine the influence of inhibition of insulin-regulated aminopeptidase/oxytocinase (IRAP) on glucose tolerance and metabolism of skeletal muscle and visceral adipose tissue in obese Zucker rats. Obese Zucker rats… read more here.
Keywords: obese zucker; zucker; metabolism; zucker rats ... See more keywords
Unveiling IL-33/ST2 Pathway Unbalance in Cardiac Remodeling Due to Obesity in Zucker Fatty Rats
Sign Up to like & getrecommendations! Published in 2023 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms24031991
Abstract: Obesity is an epidemic condition linked to cardiovascular disease severity and mortality. Fat localization and type represent cardiovascular risk estimators. Importantly, visceral fat secretes adipokines known to promote low-grade inflammation that, in turn, modulate its… read more here.
Keywords: zucker; unveiling st2; pro fibrotic; zucker fatty ... See more keywords
Obesity and Age-Related Changes in the Brain of the Zucker Lepr fa/fa Rats
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DOI: 10.3390/nu12051356
Abstract: Metabolic syndrome (MetS) is an association between obesity, dyslipidemia, hyperglycemia, hypertension, and insulin resistance. A relationship between MetS and vascular dementia was hypothesized. The purpose of this work is to investigate brain microanatomy alterations in… read more here.
Keywords: zucker; age related; ozrs; obesity age ... See more keywords