Unilateral section of the superior ovarian nerve induces first ovulation in the Zucker fatty (fa/fa) rat.
Sign Up to like & getrecommendations! Published in 2021 at "General and Comparative Endocrinology"
DOI: 10.1016/j.ygcen.2020.113636
Abstract: Abstract Hyperactivity in the sympathetic nervous system has been shown to be related to the development of ovarian pathologies. In addition, obesity has been found to be associated with multiple reproductive anomalies and is considered… read more here.
Keywords: unilateral section; ovarian nerve; superior ovarian; zucker fatty ... See more keywords
DS-7250, a Diacylglycerol Acyltransferase 1 Inhibitor, Enhances Hepatic Steatosis in Zucker Fatty Rats via Upregulation of Fatty Acid Synthesis
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DOI: 10.1177/0192623318765909
Abstract: Diacylglycerol acyltransferase 1 (DGAT1) catalyzes the final step in triglyceride synthesis. Since Dgat1 -/- mice fed a high-fat diet (HFD) are resistant to hepatic steatosis, DGAT1 inhibitors are expected to have antifatty liver effects. To… read more here.
Keywords: hepatic steatosis; fatty rats; diacylglycerol acyltransferase; zucker fatty ... See more keywords
Cardiovascular Characteristics of Zucker Fatty Diabetes Mellitus Rats, an Animal Model for Obesity and Type 2 Diabetes
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DOI: 10.3390/ijms23084228
Abstract: Zucker fatty diabetes mellitus (ZFDM) rats harboring the missense mutation (fa) in a leptin receptor gene have been recently established as a novel animal model of obesity and type 2 diabetes (T2D). Here, we explored… read more here.
Keywords: fatty diabetes; animal model; homo; zucker fatty ... See more keywords
Unveiling IL-33/ST2 Pathway Unbalance in Cardiac Remodeling Due to Obesity in Zucker Fatty Rats
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DOI: 10.3390/ijms24031991
Abstract: Obesity is an epidemic condition linked to cardiovascular disease severity and mortality. Fat localization and type represent cardiovascular risk estimators. Importantly, visceral fat secretes adipokines known to promote low-grade inflammation that, in turn, modulate its… read more here.
Keywords: zucker; unveiling st2; pro fibrotic; zucker fatty ... See more keywords