Articles with "zy12201" as a keyword



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ZY12201, A Potent TGR5 Agonist: Identification of a Novel Pan CYP450 Inhibitor Tool Compound for In-Vitro Assessment.

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Published in 2022 at "Drug metabolism letters"

DOI: 10.2174/1872312815666220315145945

Abstract: BACKGROUND Identification of clinical drug-drug interaction (DDI) risk is an important aspect of drug discovery and development owing to poly-pharmacy in present-day clinical therapy. Drug metabolizing enzymes (DME) plays important role in the efficacy and… read more here.

Keywords: inhibition; cyp; zy12201; tool compound ... See more keywords