C. elegans XMAP215/ZYG-9 and TACC/TAC-1 act at multiple times during oocyte meiotic spindle assembly and promote both spindle pole coalescence and stability
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DOI: 10.1371/journal.pgen.1010363
Abstract: The conserved two-component XMAP215/TACC modulator of microtubule stability is required in multiple animal phyla for acentrosomal spindle assembly during oocyte meiotic cell division. In C. elegans, XMAP215/zyg-9 and TACC/tac-1 mutant oocytes exhibit multiple and indistinguishable… read more here.
Keywords: zyg; oocyte meiotic; tac; spindle assembly ... See more keywords
ZYG-9ch-TOG promotes the stability of acentrosomal poles via regulation of spindle microtubules in C. elegans oocyte meiosis
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DOI: 10.1371/journal.pgen.1010489
Abstract: During mitosis, centrosomes serve as microtubule organizing centers that guide the formation of a bipolar spindle. However, oocytes of many species lack centrosomes; how meiotic spindles establish and maintain these acentrosomal poles remains poorly understood.… read more here.
Keywords: 9ch tog; elegans oocyte; zyg; acentrosomal poles ... See more keywords